G protein

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Related to G-protein: Adenylyl cyclase

G protein

[′jē ‚prō‚tēn]
(cell and molecular biology)
References in periodicals archive ?
According to the company, G-protein coupled receptors (GPCRs) are attractive drug targets in the treatment of many different conditions, playing an essential part in numerous life processes and influencing diseases.
RGS22, a novel testis-specific regulator of G-protein signaling involved in human and mouse spermiogenesis along with GNA12/13 subunits.
The report provides comprehensive information on the Sphingosine 1-Phosphate Receptor 1 (S1P Receptor 1 or Endothelial Differentiation G-Protein Coupled Receptor 1 or Sphingosine 1-Phosphate Receptor Edg-1 or CD363 or S1PR1 or CHEDG1 or EDG1), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
sup][6],[7] Telmisartan is a long-lasting and nonpeptide angiotensin II (Ang II) receptor blocker that is highly selective to angiotensin II type 1 receptors (AT1), a G-protein coupled receptor (GPCR).
said they have formed a two-year discovery collaboration focused on a single G-protein coupled receptor that plays an important role in the pathology of central nervous system disorders.
By targeting beta-arrestin, the scientists were able to turn off G-protein signaling, which stimulates bone resorption, while at the same time the b-arrestin pathway stimulated bone formation.
THE EXPRESSION OF G-PROTEIN COUPLED RECEPTOR-64 IN MICE DORSAL ROOT GANGLIA.
Heptares Therapeutics Ltd (HTL)--the drug discovery company formed in 2007 to apply recent and ongoing discoveries about the structure and function of GPCRs G-protein coupled receptors) to the design and development of its own drugs--has received substantial further seed funding from founding investors MVM Life Science Partners LLP.
Rockville, MD) has patented human G-protein chemokine receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques.
A further chapter discusses how surface membrane G-protein receptors in C.
Transfluor technology comprises cell-based fluorescent assays for imaging and G-protein coupled receptor (GPCR) studies that are used with imaging platforms, such as Molecular Devices' Discovery-1 and ImageXpress systems.