(14.) "Mas alla de este relato oficial que implica el DPA [discurso patrimonial autorizado], existen otros que emergen de la subjetividad e intersubjetividad de los habitantes que, a traves de distintas experiencias (temporales y espaciales) producen otros discursos patrimoniales, en este caso 'no autorizados' (DPNA)" (Giop
y Flores, 2017, p.
The FDA has approved alendronate, zoledronic acid (Reclast), and risedronate (Actonel) for treatment of GIOP
. More recently, raloxifene (Evista) has joined the ranks of agents shown to increase BMD in patients on long-term steroids; this came in the form of a double-blind, placebo-controlled, 12-month study (Ann.
Among the eight patients who were on the drug before referral, seven were taking it specifically for GIOP
, and one had been previously diagnosed with osteoporosis.
"We were encouraged to see that rates of testing and treatment for GIOP
among internists appear to have achieved parity with their specialist counterparts.
Thus the specification supports additional protocols that may be provided in two fundamental ways: first, GIOP
may be layered on reliable protocols other than TCP/IP.
The company said Prolia (denosumab) is approved for the treatment of glucocorticoid-induced osteoporosis (GIOP
) in men and women at high risk of fracture, osteoporotic fracture history, multiple risk factors for fracture, or patients who have failed or are intolerant to other available osteoporosis therapy.
"Complications of glucocorticoid-induced osteoporosis (GIOP
), especially fractures, can be extremely severe and may have a profoundly negative effect on the patient's quality of life," Dr.
As a result, the standard General InterORB Protocol (GIOP
) and its specification for implementation over TCP/IP, the Internet InterORB Protocol (IIOP), were added to version 2.0 of the CORBA specification, which was published in 1995.
- Thousand Oaks, California-based human therapeutics developer Amgen's (NASDAQ: AMGN) supplemental Biologics License Application (sBLA) for Prolia (denosumab) for the treatment of patients with glucocorticoid-induced osteoporosis (GIOP
) has been accepted for review by the US Food and Drug Administration, the company said.
For servants executing remotely, a CORBA-compliant  ORB Core communicates via the Internet Inter-ORB Protocol (IIOP), which is a version of the General Inter-ORB Protocol (GIOP
) that runs atop the TCP trans port protocol.
Human therapeutics company Amgen (NASDAQ:AMGN) said on Monday that it has filed its supplemental Biologics License Application (sBLA) for Prolia with the US Food and Drug Administration (FDA) for review for the treatment of glucocorticoid-induced osteoporosis (GIOP
), the most common form of secondary osteoporosis.
IIOP is a TCP/IP-specific instance of CORBA's General Inter-ORB Protocol (GIOP