# factor

(redirected from GM-CSF)
Also found in: Dictionary, Thesaurus, Medical, Legal, Financial, Acronyms, Wikipedia.
Related to GM-CSF: interleukin, Cytokines, Sargramostim

## factor,

in arithmetic, any number that divides a given number evenly, i.e., without any remainder. The factors of 12 are 1, 2, 3, 4, 6, and 12. Similarly in algebra, any one of the algebraic expressions multiplied by another to form a product is a factor of that product, e.g., a+b and ab are factors of a2b 2, since (a+b)(ab)=a2b2. In general, if r is a rootroot,
in mathematics, number or quantity r for which an equation f(r)=0 holds true, where f is some function. If f is a polynomial, r is called a root of f; for example, r=3 and r
of a polynomialpolynomial,
mathematical expression which is a finite sum, each term being a constant times a product of one or more variables raised to powers. With only one variable the general form of a polynomial is a0xn+a1x
equation f(x)=0, then (xr) is a factor of the polynomial f(x).

## factor

[′fak·tər]
(mathematics)
For an integer n, any integer which gives n when multiplied by another integer.
For a polynomial p, any polynomial which gives p when multiplied by another polynomial.
For a graph G, a spanning subgraph of G with at least one edge.
(statistics)
A quantity or a variable being studied in an experiment as a possible cause of variation.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

## factor

1. Maths
a. one of two or more integers or polynomials whose product is a given integer or polynomial
b. an integer or polynomial that can be exactly divided into another integer or polynomial
2. Med any of several substances that participate in the clotting of blood
3. Law, Commerce a person who acts on another's behalf, esp one who transacts business for another
4. former name for a gene
5. Commercial law a person to whom goods are consigned for sale and who is paid a factorage
6. (in Scotland) the manager of an estate
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005

## factor

A quantity which is multiplied by another quantity.

## factor

A number that divides evenly into another number. For example, 3 and 4 are factors of 12. See factorial and IFP.
Copyright © 1981-2019 by The Computer Language Company Inc. All Rights reserved. THIS DEFINITION IS FOR PERSONAL USE ONLY. All other reproduction is strictly prohibited without permission from the publisher.
References in periodicals archive ?
Additionally, in our study Gencydo[R]was found to inhibit IgE-mediated release of GM-CSF. GM-CSF is a cytokine that promotes eosinophil activation and survival.
GM-CSF regulates protein and lipid catabolism by alveolar macrophages.
Doctors also hope the GM-CSF genes in the cells will boost the patient's immune system and lymphocytes will attack any cancer cells remaining in his body.
But approval for GM-CSF, the most thoroughly tested, appears "very close," says Jules E.
According to the company, Unituxin is a GD2-binding monoclonal antibody indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA) for high-risk neuroblastoma.
The company added that GM-CSF is a critical pro-inflammatory cytokine that plays a pivotal role in tissue inflammation and destruction in autoimmune and inflammatory diseases.
FGF-basic, GM-CSF, IP-10, IFN-[gamma], IL-1[alpha], IL-1[beta], IL-2, IL-4, IL-5, IL-6, IL-10, IL-12, IL-13, IL-17, KC, MIP-1-[alpha], MCP-1, MIG, and TNF-[alpha] were evaluated with the mouse cytokine magnetic 20-Plex panel (Novex[R] by Life Technologies, USA) with the immunoassay Luminex Magpix Platform (Luminex Corporation, USA), as previously described (8).
On the other hand, studies revealed that in animals the G-CSF and granulocyte macrophage-colony stimulating factor (GM-CSF) may mobilize endothelial progenitor cells19-20.
The Penn State-research studied the survival and lung function of mice with influenza in the lab and found that GM-CSF - a protein that modifies the immune response to the flu, may also help reduce lung inflammation and improve survival during influenza.
Generation of BMDCs by prolonged culture is based on the differentiation of DCs with either granulocyte-macrophage colony-stimulating factor (GM-CSF) alone [6] or in combination with Interleukin-4 (IL-4) [6,18,19].

Site: Follow: Share:
Open / Close