Beltran-Partida et al., "The effects of (--)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER
)," Pharmacological Research, vol.
New evidence suggests that GPER
also regulates mitochondrial function by preventing opening of the mitochondrial permeability transition pore, mediated by a nongenomic mechanism via Erk activation .
By 6 months of age GPER
knockouts of both genders were obese, without changes in food intake or locomotor activity, and insulin resistant but only females exhibited glucose intolerance.
is a member of the 7-transmembrane spanning G protein-coupled receptor (GPCR) superfamily, structurally unrelated to the nuclear receptor family members ER[alpha] and ER[beta] [16, 17].
Doing so for the first in 2005 yields a population of 4.1 Gper
and a GDP of 54.8 G$/year, numbers we associate with the estimates in the IEA dataset of world consumption of light from grid electricity in 2005.
I E, 6A, 9B GPER
Pseudo-Gunnera G macrophylla Blume 3C, 8A, 9A, 9E GMAC Other families Aextoxicaceae Aextoxicon punctatum Ruiz & Pav.
36 7 - Security 96 97 95 Al-Quresh 70 57 31 City 36 33 75 Century - 7 42 Ali Paper 99 80 97 Flying Board - 11 65 Kabir 77 89 105 Bahawalpur 30 - - Source: Pakistan Pulp Paper & Broad Makers Association Karachi Earning per Share of Paper & Board Companies (Earnin gper
An exogenous chemical may exert estrogenic effects by both classical nuclear estrogen receptors (ERs) and non-genomic G protein-coupled estrogen receptor (GPER
) pathways (Shanle and Xu 2011).
Among them, estrogen activates the estrogen receptor- (ER-) [alpha], ER-[beta], and G protein-coupled estrogen receptor (GPER
) to regulate physiological pathways in various tissues, such as the hypothalamus, liver, bone, and islets [1,40].
The effects of estrogen are mediated by two types of estrogen receptors: nuclear estrogen receptors (ER-a and ER-[beta]), which are members of the nuclear receptor family of intracellular receptors, and membrane estrogen receptor (GPER
or G-protein-coupled estrogen receptor) .
ldentification of the estrogen receptor GPER
in neoplastic and non-neoplastic human testes.