Although there was some thought that NF-kB activation could lead to a decrease in extracellular matrix degradation capacity, in turn leading to impaired angiogenesis , NF-kB transcription factors have been found to be effectors of the Rho family, including molecules such as the GTP-binding protein
RAC1, during inflammation [19, 36].
Rho-associated kinase (Rho kinase/ROCK), identified as a Rho GTP-binding protein
, is a downstream effector of the small GTP-binding protein
Vesicle endocytosis requires GTP hydrolysis by the GTP-binding protein
dynamin, which participate in fission of the nerve terminal plasma membrane to reform vesicles.
Ephedra monosperma had mostly degradome proteins (profilins, desiccation-related protein, the GTP-binding protein
RAN-1, and ceramidase) and had only two secretome proteins that we could detect in this initial comparative study--serine carboxypeptidase and glucan endo-1,3-[beta]-glucosidase.
Among these, the RasD2 gene, encoding a small GTP-binding protein
RHES, is predominantly expressed in the striatal region of the brain and is involved in striatal function .
CgtA is a highly conserved essential GTP-binding protein
, coded by the cgtA gene, belonging to Obg subfamily in prokaryotes (8).
Results of BLAST search performed with human EGF against the non redundant mycobacterial protein database at NCBI Accession Protein Name E-Value Number NP_302390 Probable multidrug resistance pump 0.022 NP_301513 GTP-binding protein
LepA 0.40 NP_301554 Putative -alanyl-D-alanine carboxypeptidase 2.2 NP_302118 heat shock protein 90 2.4 NP_302586 UDP-N-acetylenolpyruvoylglucosamine reductase 4.4 NP_301491 6-phosphogluconolactonase 6.5 NP_301739 Possible ATP/GTP-binding protein 7.8 NP_301890 Mycocerosic acid synthase 8.8 Table 3.
Lafuse, W.P., Brown, D., Castel, L., Zwilling, B.S., 1995 Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein
Rac-1 on its inhibitor RhoGDI-1.
164) includes rhodopsin, the pigment that absorbs light; GTP-binding protein
, or transducin; an enzyme called rhodopsin kinase; another called S-antigen; and a retinoid-(vitamin A-) binding protein.
Hall, "The small GTP-binding protein
rac regulates growth factor-induced membrane ruffling," Cell, vol.
(1982) Functional reconstitution of beta-adrenergic receptors and the stimulatory GTP-binding protein
of adenylate cyclase.