Galactosamine


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galactosamine

[gə‚lak′tō·sə‚mēn]
(biochemistry)
C6H14O5N A crystalline amino acid derivative of galactose; found in bacterial cell walls.

Galactosamine

 

(also chondrosamine, 2-amino-2-deoxygalactose), an amino sugar; first isolated from cartilaginous tissue. A strong base, readily soluble in water, and optically active.

An important derivative of glactosamine is N-acetyl-galactosamine, which is present as a repeating unit in chondroitin; N-acetylgalactosamine sulfate is present in chondroitin sulfates and keratosulfate. Along with glucosamine, galactosamine is a structural element in the polysaccharide of group-specific mucoids in humans and animals and also as part of the specific polysaccharide of pneumococci.

References in periodicals archive ?
Isolation, structure, synthesis, and bioactivity ofa novel putative insulin mediator: a galactosamine chiro-inositol pseudo-disaccharide Mn2+ chelate with insulin-like activity," Journal of Medicinal Chemistry, vol.
Hepatoprotective activity of andrographolide against galactosamine & paracetamol intoxication in rats.
These enzymes have been shown to hydrolyse heparan sulphate, which consists of N-acetylated or N sulphated glucosamine or galactosamine linked to glucoronic or iduronic acid.
D-chiro-Inositol is a component of galactosamine D-chiro-inositol, a putative insulin mediator (Larner et al.
The test screens a mucus sample for a specific galactosamine that is secreted in excessive amounts by tumors.
Andrographis was also found to be superior to silymarin in protecting the liver against paracetamol toxicity [16] and against paracetamol and galactosamine.
In this study, mice were administered galactosamine and endotoxin (Gal/ET), chemical agents that are used to induce endotoxemia resulting in liver failure due to cell death.
In these experiments 13-15 day old neonatal rats (Wistrar), were sensitized to LPS by injecting D + galactosamine (600 mg/kg).
4], galactosamine (Galc), and phalloidin and strongly inhibited the activity of 5-lipoxygenase in porcine leukocytes.
Sharma, 1990); hepatoprotective activity of andrographolide against galactosamine and paracetamol intoxication in rats (Handa, S.
Assay method for anti-hepatoprotective using galactosamine induced cytotoxicityin primary cultured hepatocytes.