Galanthamine


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Related to Galanthamine: Galantamine, Galantamine hydrobromide

Galanthamine

 

a drug that is one of the anticholinesterase agents; an alkaloid contained in some types of snowdrop (Galanthus) and snowflake (Leucoium). A solution of galanthamine is injected hypodermically to cure myasthenia, myopathy, and infantile cerebral paralysis. It is also used during the restoration period of poliomyelitis. It is an antidote for curare.

References in periodicals archive ?
We performed calibration curve of galanthamine in concentration range from 0.156 to 2.5 [micro]M with limit of detection calculated to 149 nM and quantification limit of 0.5 [micro]M was achieved (Figure 6).
Harvey, "The pharmacology of galanthamine and its analogues," Pharmacology and Therapeutics, vol.
Mae galanthamine yn helpu ymladd ac arafu Alzeimher's.
Gucnard et al., "The complex of a bivalent derivative of galanthamine with torpedo acetyl-cholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design, " Journal of the American Chemical Society, vol.
Table 2 shows the five species that showed higher inhibition activity, in comparison to commonly used drug galanthamine (([IC.sub.50] = 0.37 x [10.sup.-3] mg/mL), which is is considered to be the most effective compound in the treatment of Alzheimer's disease.
Treating Alzheimer's with the cheaper alternative of galanthamine, therefore, has the potential to improve the lives of thousands of people.
Effects of four non-cholinergic cognitive enhancers in comparison with tacrine and galanthamine on scopolamine-induced amnesia in rats.
Galanthamine Synaptech Referred by BGH on Case 15 W 36/08 Sitagliptin 28/1/10 Referred by EWCA on Medeva's SPC Various combinations 23/6/10 application of antigens Case Issue C-66/09 Transitional provisions for Lithuania (Advocate General Opinion 25/2/10) C-195/09 What constitutes a first Marketing Authorisation in the EU C-427/09 What constitutes a first Marketing Authorisation in the EU Referred by BGH on Can an SPC have negative or zero 28/1/10 term so as to allow a paediatric extension to be sought?
(12) Several drugs commonly used today for AD treatment were developed from local and traditional medicine, such as galanthamine, an AChE-I which was developed from alkaloids in 'Snowdrop'.
They will be harvested and processed for galanthamine, a chemical which scientists believe can alleviate the symptoms of Alzheimer's disease.
A species of the Welsh national flower contains galanthamine. which can fight memory loss, say Cardiff University researchers who now want huge daffodil farms set up in the Black Mountains.