gap junction

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gap junction

[′gap ‚jəŋk·shən]
(neuroscience)
An intercellular junction composed of cylindrical channels connecting adjacent cells; considered to be a low-resistance pathway for intercellular communication. Also known as communicating junction; nexus.
References in periodicals archive ?
Regulation of gap junctions in porcine cumulus-oocyte complexes: contributions of granulosa cell contact, gonadotropins, and lipid rafts.
Gap junctions have intercellular pores that facilitate the passage
These phosphoisoforms are believed to reflect the localization of Cx43, patency of the gap junction, and ability to participate in epithelial-stromal communication [51].
Having demonstrated that a siRNA against Cx43 is able to block cell-to-cell communication via gap junctions, we next evaluated the effect of this siRNA on CFTR expression and function.
[I.sub.stim] is the stimulus current applied to myocyte membrane, [I.sub.gap] is the current that flows through the gap junction between the myocyte and each fibroblast, n is the total number of fibroblasts, and [G.sub.gap] represents the gap junction conductance.
Nicholson, "Selective transfer of endogenous metabolites through gap junctions composed of different connexins," Nature Cell Biology, vol.
Gap junctions, made up of connexons; sustain the integral function of cells by permitting communication between them.
Global modulation mediated by gap junctions. It has been shown that retinal gap junctions (40,41) contribute to the neural noise reduction that is mediated by signal transmission far beyond each classical RF.
Additionally, the effect of Wenxin Granule on Cx43 and Cx45, those involved in gap junction pathway, was also observed in the present study.
Effect of PAR on Gap Junctions. To confirm the increased level of gap junctions evidenced in the 2D experiments, cell-to-cell communications were assessed by injecting the fluorescent dye, lucifer yellow (LY), in the 3D model after PAR treatment (Figure 7).
Rieger, "Is intercellular communication via Gap junctions required for myoblast fusion?" Cell Communication and Adhesion, vol.