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Related to Gastrin: enterogastrone, somatostatin, secretin


A polypeptide hormone secreted by the pyloric mucosa which stimulates the pancreas to release pancreatic fluid and the stomach to release gastric acid.



a polypeptide hormone secreted by the mucous membrane of the pylorus of the stomach; it is secreted when the pylorus is stretched or acted on by chemical stimulants (for example, products of the decomposition of food) or impulses from the vagus nerves. Gastrin increases the secretion of gastric and pancreatic juices, as well as of bile, and alters the tone and motility of the stomach and intestines. An increase in the hydrochloric-acid content of the pylorus (when acidic gastric juice enters it) inhibits the secretion of gastrin. Two kinds of gastrin, which are very similar in structure and physiological properties, have been distinguished. Gastrin has been synthesized chemically.

References in periodicals archive ?
Blood was centrifuged at 3000 rpm for 10 min and the supernatant was used for determination of gastrin levels using a Rat Gastrin ELISA kit, following the manufacturer's instructions.
Alongside the clarification of the diagnostic indication for gastrin measurement, several analytical issues exist.
The plasma concentrations of CCK, secretin, PP, gastrin and GIP were all positively or negatively correlated with the specific activity of chymotrypsin (p<0.
Serum levels of gastrin, motilin and PP also remained the same at all times in both groups.
Gastrin enhances the angingenic potential of endothelial cells via modulation of heparin-binding epidermallike growth factor.
Comparison of the kinetic disposition of and serum gastrin change by lansoprazole versus rabeprazole during an 8-day dosing scheme in relation to CYP2C19 polymorphism.
Transition's gastrin based therapies, including the lead compound TT-223, which
The mice lacking gastrin also had fewer stomach-lining cells die off, which is a normal, tumor-suppressing action.
Glucagon, gastrin, and carcinoid tumors of the duodenum, pancreas, and stomach: Polypeptide "apudomas" of the foregut.
Recent findings have shown that inhibiting gastrin not only inhibits cell growth, proliferation and metastasis directly, but also "unblocks" a central pathway leading to cell-suicide (apoptosis).
Tolerance during 8 days of high-dose H2-blockade: Placebo-controlled studies of 24-hour acidity and gastrin.