DNA microarray

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Related to Gene chip technology: DNA microarray, Microarray analysis, CDNA microarray

DNA microarray

[¦dē¦en¦ā ′mī·krō·ə‚rā]
(cell and molecular biology)
A microscopic spot containing identical single-stranded polymeric molecules of deoxyribonucleotides (DNAs), usually oligonucleotides or complementary DNAs, attached to a solid support (such as a membrane, a polymer, or glass) used to simultaneously analyze the expression levels of the corresponding genes.
References in periodicals archive ?
In the present study, we screened out DEGs of the duodenum using the gene chip technology and performed functional and KEGG pathway enrichment analysis.
Gene chip technology can be used in large-scale, high throughput and parallel analysis of thousands of genes, through the design of different probe array, using a specific analysis method can make the technology has a wide variety of different applications.
Muhammad Furqan Bari, Research Consultant Pathology emphasized that as this is an era of gene chip technology therefore we need to develop our own distinct genetic profile for targeted therapy in future.
Additionally, Davis and his research colleagues looked at the effect of walnuts on gene activity in the prostate tumors using whole mouse gene chip technology, and found beneficial effects on multiple genes related to controlling tumor growth and metabolism.
These two studies show the power of applying gene chip technology to skin research to take a look at the entire pattern of gene expression--both upregulation and downregulation--effected by an ingredient at different time points.
The SMART (switching mechanism at the 5' end of RNA templates of reverse transcriptase) method (1, 2), in combination with PCR, has been used to amplify minute samples obtained from sources such as laser capture microdissections and biopsies for gene expression analysis using oligonucleotide microarray gene chip technology (3-7).