DNA microarray

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Related to Gene chip technology: DNA microarray, Microarray analysis, CDNA microarray

DNA microarray

[¦dē¦en¦ā ′mī·krō·ə‚rā]
(cell and molecular biology)
A microscopic spot containing identical single-stranded polymeric molecules of deoxyribonucleotides (DNAs), usually oligonucleotides or complementary DNAs, attached to a solid support (such as a membrane, a polymer, or glass) used to simultaneously analyze the expression levels of the corresponding genes.
References in periodicals archive ?
Gene chip technology can be used in large-scale, high throughput and parallel analysis of thousands of genes, through the design of different probe array, using a specific analysis method can make the technology has a wide variety of different applications.
Muhammad Furqan Bari, Research Consultant Pathology emphasized that as this is an era of gene chip technology therefore we need to develop our own distinct genetic profile for targeted therapy in future.
These two studies show the power of applying gene chip technology to skin research to take a look at the entire pattern of gene expression--both upregulation and downregulation--effected by an ingredient at different time points.
The SMART (switching mechanism at the 5' end of RNA templates of reverse transcriptase) method (1, 2), in combination with PCR, has been used to amplify minute samples obtained from sources such as laser capture microdissections and biopsies for gene expression analysis using oligonucleotide microarray gene chip technology (3-7).
As gene chip technology moves into clinical use, detecting a large number of resistance determinants soon after a patient is admitted to the hospital should be possible.
Studies using innovative statistical or technical methods, such as quantitative trait locus (QTL) analysis or gene chip technology, are highly encouraged.