genetic load

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genetic load

[jə¦ned·ik ′lōd]
(genetics)
The reduction in fitness of a diploid population due to new mutant genes and those already in the gene pool.
References in periodicals archive ?
The ability to ameliorate some of these deleterious effects by altering the familial environment will conflict parents who might have to choose between providing an environment that alleviates one child's genetic burden at the expense of another's.
From the medical point of view CA is a multifactorial (polygenic) disease--with genetic burden.
"Diagnosis can be made rapidly in the clinic and one can get on with the business of counseling the families and doing the best one can with a terrible genetic burden," he said.