genetic load

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genetic load

[jə¦ned·ik ′lōd]
(genetics)
The reduction in fitness of a diploid population due to new mutant genes and those already in the gene pool.
References in periodicals archive ?
Diagnosis can be made rapidly in the clinic and one can get on with the business of counseling the families and doing the best one can with a terrible genetic burden," he said.
One growing problem posed by modern medical technologies is that more people suffering from genetic defects will survive to reproduce, thus increasing the genetic burden for the future.
05% of the genome, comprehensive gene sequencing captures the entire coding region of an individual's genes, collectively known as the exome, enabling the detection of rare variants - mutations that many scientists believe account for the majority of the genetic burden of disease.