George Hoyt Whipple

Whipple, George Hoyt


Born Aug. 28, 1878; died Feb. 1, 1976. American physician and pathologist.

Whipple graduated from Yale University in 1900 and received the M.D. degree from Johns Hopkins University in 1905. He was a professor at the University of California from 1914 to 1921 and a professor of pathology at the University of Rochester from 1921 to 1955. Whipple’s main works dealt with anemias, pigment metabolism, liver and pancreatic lesions, tuberculosis, and parasitic diseases. Whipple was awarded a Nobel Prize in 1934 jointly with G. R. Minot and W. Murphy for discovering the role of the liver in hematopoiesis and for the use of liver therapy in pernicious anemia.


Corner, G. W. George Hoyt Whipple and His Friends. Philadelphia-Montreal, 1963.
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Study co-author Chawnshang Chang, the George Hoyt Whipple Distinguished Professor of Pathology at the University of Rochester Medical Center, and colleagues, showed that the androgen receptor (AR), a protein that mediates male sex hormones, promotes liver cancer when hepatitis B is present by altering DNA replication of the virus.
The American pathologist George Hoyt Whipple (1878-1976) induced an artificial anemia in dogs by bleeding them, then followed the manner in which new red blood corpuscles were formed.