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A discrete nodular lesion of inflammatory tissue in which granulation is significant.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Giant cell reparative granuloma is a benign lesion with limited growth potential, usually treated with simple curettage.
Giant cell reparative granuloma of short tubular bones of the hands and feet.
(9.) UA Shah, AK Shah, S Kumar Giant cell reparative granuloma of the jaw : A case Report Ind J Radiol Imag 2006 16 (4):677 678.
"Solid" variant of aneurysmal bone cyst (extragnathic giant cell reparative granuloma) in the axial skeleton and long bones.
Giant cell reparative granuloma outside the jaw bone.
They found p63 overexpression in roughly 30% of chondroblastomas and aneurysmal bone cysts, but not in giant cell reparative granulomas, pigmented villonodular synovitides, or tenosynovial giant cell tumors.
The 2 previous studies did not show evidence of p63 overexpression in cases of tenosynovial giant cell tumors, giant cell reparative granulomas, or pigmented villonodular synovitides, and the degree of p63 expression in aneurysmal bone cysts and chondroblastomas was significantly lower.

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