In addition, proinflammatory cytokines IL-1[beta] and IL-6 are expressed in type-I glomus cells (Table 1) and also in type-II cells of the carotid body [29, 30].
Also, proinflammatory cytokines significantly enhance the intracellular calcium response to hypoxia in the chemosensitive glomus cells  and the carotid chemoafferent activity [19, 29].
The increased expression of proinflammatory cytokines and receptors is localized to lobules of chemosensitive type-I glomus cells and the proportional amount of the cells expressing cytokines and cytokine receptors is significantly increased by a couple of days of intermittent hypoxia and it remains at an elevated level in hypoxia up to a week [18, 30, 52, 62].
Since glomus cells share many features of smooth muscle cells, intravascular spread of glomus tumors may be similar to that seen in intravascular leiomyomatosis.
In summary, the multiple glomus tumors in the chest wall of this young man are best categorized as glomangiomyomas, owing to the presence of prominent smooth muscle bundles admixed with glomus cells. Such cases of multiple glomangiomyomas are rare, and to my knowledge have not been described before in the chest wall.
The infiltrate composed mainly of monomorphic round or polygonal glomus cells with round or ovoid nucleus and scant eosinophilic cytoplasm.
DISCUSSION: Glomus tumors are thought to represent neoplastic proliferations of modified smooth muscle cells, called glomus cells, located in the walls of the Sucquet-Hoyer canal, a specialized arteriovenous anastomosis found most often in the fingers and play an important role in thermoregulation.