glucose-6-phosphate dehydrogenase

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glucose-6-phosphate dehydrogenase

[′glü‚kōs ¦siks ′fäs‚fāt dē‚hī′drä·jə‚nās]
(biochemistry)
The mammalian enzyme that catalyzes the oxidation of glucose-6-phosphate by TPN+(triphosphopyridine nucleotide).
References in periodicals archive ?
FFA, free fatty acid; FAT fatty acid translocase; ACC[alpha], acetyl-CoA carboxylase [alpha]; FAS, fatty acid synthase; ICDH, isocitrate dehydrogenase; G6PDH, glucose 6-phosphate dehydrogenase; MDH, malate dehydrogenase; ME, malic enzyme; TC, triglyceride; CPT1A, carnitine palmitoyl transferase 1A; ATGL, adipose triglyceride lipase; HSL, hormone-sensitive lipase; TCA, tricarboxylic acid cycle; PPP, pentose phosphate pathway; P/C, pyruvate/citrate; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PEMT, phosphatidylethanolamine N-methyltransferase; VLDL, low-density lipoprotein.
Functional properties of two mutants of human glucose 6-phosphate dehydrogenase, R393G and R393H, corresponding to the clinical variants G6PD Wisconsin and Nashville.
Engel, "Purification and detailed study of two clinically different human glucose 6-phosphate dehydrogenase variants, G6PDPlymouth and G6PDMahidol: evidence for defective protein folding as the basis of disease," Molecular Genetics and Metabolism, vol.
Fructose 1,6-di phosphatase, phosphofructokinase and glucose 6-phosphate dehydrogenase from fermenting and nonfermenting yeasts.
Maleimide as an inhibitor in measurement of erythrocyte glucose 6-phosphate dehydrogenase activity.
These include hemolysis in individuals with glucose 6-phosphate dehydrogenase deficiency after exposure to antimalarial drugs and other oxidants (Motulsky 1972); increased risk of emphysema from cigarette smoking in individuals with [[alpha].sub.1] antitrypsin deficiency (Eriksson 1965; Lieberman et al.