FFA, free fatty acid; FAT fatty acid translocase; ACC[alpha], acetyl-CoA carboxylase [alpha]; FAS, fatty acid synthase; ICDH, isocitrate dehydrogenase; G6PDH, glucose 6-phosphate dehydrogenase
; MDH, malate dehydrogenase; ME, malic enzyme; TC, triglyceride; CPT1A, carnitine palmitoyl transferase 1A; ATGL, adipose triglyceride lipase; HSL, hormone-sensitive lipase; TCA, tricarboxylic acid cycle; PPP, pentose phosphate pathway; P/C, pyruvate/citrate; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PEMT, phosphatidylethanolamine N-methyltransferase; VLDL, low-density lipoprotein.
Engel, "Purification and detailed study of two clinically different human glucose 6-phosphate dehydrogenase
variants, G6PDPlymouth and G6PDMahidol: evidence for defective protein folding as the basis of disease," Molecular Genetics and Metabolism, vol.
These include hemolysis in individuals with glucose 6-phosphate dehydrogenase
deficiency after exposure to antimalarial drugs and other oxidants (Motulsky 1972); increased risk of emphysema from cigarette smoking in individuals with [[alpha].sub.1] antitrypsin deficiency (Eriksson 1965; Lieberman et al.