glucuronide

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glucuronide

[glü′kyu̇r·ə‚nīd]
(biochemistry)
A compound resulting from the interaction of glucuronic acid with a phenol, an alcohol, or an acid containing a carboxyl group. Also known as glycuronide.
References in periodicals archive ?
detected in hair [75], it would be reasonable to use the glucuronides of
The major WEL metabolites were glucuronide conjugates, which had a quite different ionization efficiency from WEL in (+)ESI mode.
It was observed that the majority of silymarin compounds were excreted within 24 hours of ingestion, but substantial amounts of glucuronides, sulpho-glucuronides and diglucuronides were excreted for up to 48 hours.
Although sulfates were well hydrolysed as glucuronides in the body, sulfates (especially, ICHQ sulfate) resisted enzymatic hydrolysis in vitro by mitochondrialysosomal and microsomal enzymes in both liver and kidney in contrast to glucuronides to them (Ref Table 3).
As the comparative method, LC-MS/MS was deemed the gold standard and used to categorize samples that should test positive for opiates (morphine, hydromorphone, codeine, hydrocodone, 6-monoacetylmorphine, or glucuronide metabolites), oxycodone (oxycodone, oxymorphone, or oxymorphoneglucuronide), or methadone.
Qualifier ions Isomers (m/z) (m/z) Silychristin 481 125 Silydianin 481 125 SilybinAand B 481 125 Isosilybin A and B 481 125 Silymarin 657 481, 125 16 glucuronides Silymarin sulphate 737 657, 561, 481, 7 glucuronides 125 Silymarin 833 657, 481, 125 8 diglucuronide
Most BPA was found in the urine as the glucuronide conjugate.
Similarly, MRM chromatograms of liver, lungs and pancreas indicated the presence of glucuronides, sulfates and monohydroxylated metabolites of puerarin (Figs.
It is worth noting that the signal of carboxylic acid C6' carbon was not observed, as is frequently the case for glucuronides.
Unconjugated THC and 11-OH-THC are not detected or detected in low concentrations (11-OH-THC only) in urine and require enzymatic or tandem enzymatic-alkaline hydrolysis to cleave glucuronides (19,23-24).