Mitochondria-rich cell (CRM), notice the highlighted area, the plasma membrane exposed to the environment, covered by a glycocalix
Zeta potential has been suggested to play an important role in particle uptake because the surface of the intestinal mucosa is negatively charged owing to the presence of glycocalix
Furthermore, these phage-derived enzymes may have a greater potential as therapeutic agents against biofilm formation, as the structural backbone of glycocalix
is composed of bacterial EPS [72, 73].
A part of the infused plasma substitute or the protein solution used disappears into the "endothelial surface plasma layer" (Glycocalix
) and another part leaves the circulation.
Glomerular endothelial glycocalix
constitutes a barrier to protein permeability.
(1994) proposed that the mechanism of absorption enhancement was a combination of mucoadhesion and a loosening effect on the tension of the tight junctions through ionic interactions with negatively charged groups of glycocalix
. However, the polymer was only soluble in an acidic environment in which the pH was less or if the order of the pK[.sub.a] value of chitosan (5.5-6.5), which restricted its application to the absorption enhancer seriously.
Weigand, "Sepsis-induced degradation of endothelial glycocalix
," The Scientific World Journal, vol.