glycosyltransferase

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glycosyltransferase

[‚glī·kō·sil′tranz·fə‚rās]
(biochemistry)
Any of a group of enzymes that participate in the biosynthesis of glycoproteins by transferring one sugar at a time from suitable donors to particular acceptors.
References in periodicals archive ?
These enzymes, called glycosyltransferases (GTs), transfer sugar molecules.
12) Notably, purified Arabidopsis HPAT1 and HPAT2 showed no sequence similarity to any known functionally characterized proteins, which is probably why HPAT escaped similarity-based searches for glycosyltransferases.
Specific topics include glycosyltransferases and glycan-processing enzymes, proteoglycans and sulfated glycosamingoglycans, the discovery and classification of glycan-binding proteins, glycans in acquired human diseases, and the chemoenzymatic synthesis of glycans and glycoconjugates.
In this transcriptome, the key role of glycosyltransferases and the main players involved in signal transduction, biosynthesis and deactivation of gibberellic acid has been demonstrated in the resistance reaction.
The EXT genes encode glycosyltransferases, catalyzing heparan sulfate polymerization (2).
During an acute-phase response, not only are concentrations of serum acute-phase glycoproteins altered, but their glycan structures are also dynamically modified by circulating glycosidases and glycosyltransferases (5, 6).
M2 PHARMA-January 15, 2015-BellBrook Labs Launches High Throughput Screening Assay for Glycosyltransferases
Novel functions for glycosyltransferases Jhp0562 and GalT in Lewis antigen synthesis and variation in Helicobacter pylori.
Glycoengineered alemtuzumab, made in CHO cells transfected with glycosyltransferases to change glycosylation to being more comparable to that of production in rat cells, showed higher antibody-dependent cell-mediated cytotoxicity compared to the wild type drug.
In addition, 2 nonsynonymous substitutions were observed in the capsule biosynthesis genes csiC/cskC and csiD/cskD, for which the deduced amino acid sequence encoded putative glycosyltransferases belonging to families 1 and 2, respectively.
Contributions of three glycosyltransferases to sucrose-dependent adherence of Streptococcus mutans.