glyoxylic acid

(redirected from Glyoxylate)
Also found in: Medical.

glyoxylic acid

[¦glī‚äk¦sil·ik ′as·əd]
(biochemistry)
CH(OH)2COOH An aldehyde acid found in many plant and animal tissues, especially unripe fruit.
References in periodicals archive ?
Song, "Can the glyoxylate pathway contribute to fat-induced hepatic insulin resistance?" Medical Hypotheses, vol.
Stefanescu, "Magnetic characterization of nanocrystalline Ni-Zn ferrite powder prepared by the glyoxylate precursor method," Journal of Physics D, vol.
isocitratelyase, iCL, of glyoxylate pathway) and glyconeogenesis genes (like phosphorylase and sucrose synthase, SS) were limitedly affected by cold stress (Fig.3B7, J and K).
Now a group from The Scripps Research Institute has shown the plausibility of an alternative pathway to those sugars called the glyoxylate scenario, which may push the field of pre-life chemistry past the formose reaction hurdle.
DCA is primarily biotransformed to glyoxylate by the bifunctional enzyme glutathione transferase zetal and maleylacetoacetate isomerase (GSTzl/ MAAI), which also catalyzes the penultimate step in the phenylalanine and tyrosine catabolic pathway.
Succinyl-CoA is converted to acetyl-CoA that is fed back into the cycle, with the net result of generating glyoxylate as the carbon fixation product, which is converted to pyruvate (Herter et al., 2002).
(2001) reported that EG decreased the ATP content of proximal tubular segments isolated from the mouse kidney via their metabolites, glyoxylate and glycoaldehyde.
Primary hyperoxaluria (PH) is a metabolic disorder caused by deficiency of either the liver-specific enzyme alanine:glyoxylate aminotransferase (AGT) for PH type 1 (PH1) or glyoxylate reductase/hydroxypyruvate dehydrogenase (GR/HPR) for PH type 2 (PH2).
The presence of ureidoglycolate urealyase or ureidoglycine aminohydrolase further breaks ureidoglycolate into glyoxylate. The presence of ureidoglycolate urea-lyase activity demonstrates the existence of a urea-producing pathway for ureide catabolism in chickpea.
Yudin and co-workers Subramanian Pandiaraja and Gang Chen, along with crystallographer Alan Lough have recently reported a study of the behaviour of [F.sub.8]BINOL in the Ti-catalyzed glyoxylate ene reaction (eq.
tuberculosis gets its energy from a pathway called the glyoxylate shunt.
lutzii undergoes a global metabolic switch towards gluconeogenesis and ethanol production supported by precursors (acetyl-CoA, pyruvate, oxaloacetate, and succinate) from 6-oxidation, tricarboxylic acid (TCA), and glyoxylate cycles as a mechanism to adapt to carbon-starving conditions and survive in the hostile environment during macrophage infection.