Aspiration pneumonia due to polyethylene glycol-electrolyte solution (Golytely
) treated by bronchoalveolar lavage.
Although both agents showed adequate bowel cleansing in a prospective, randomized, blinded clinical trial, GoLytely
achieved better cleansing of the overall bowel and three individual segments of the colon, as measured by the Ottawa Bowel Preparation Scale (OBPS) score, said Dr.
Braintree Laboratories pioneered the first gastrointestinal lavage in 1984 with the introduction of GoLYTELY
(PEG-3350 and electrolytes for oral solution), which was soon adopted as a standard prepping procedure prior to colonoscopy.
Milwaukee, WI; GoLYTELY
, Braintree Laboratories, Inc., Braintree, MA), because with the latter, more residual fluid remains and retained fluid may obscure polyps at CT colonography.
5.) This is accomplished using either a preparation kit (eg, Fleet Prep Kit 1, Fleet Pharmaceuticals, Lynchburg, Va) or a polyethylene glycol (PEG) electolyte solution (eg, GoLytely
, Braintree Laboratories, Braintree, Mass).
Table 4 Number of subjects using different types of laxatives Prescribed Over the counter Metamucil 0 2 Senakot 0 2 Durolax 0 4 Agarol 1 3 NuLax 0 2 Coloxyl 2 0 Alvacol 1 0 Epsom Salts 0 1 Golytely
1 0 Table 5 Mean daily consumption of serves of cereals, vegetables and fruits in constipated and not-constipated male subjects (n = daily) Number of serves Cereals Vegetables Fruit Male subjects 3.6 3.4 2.2 Functionally constipated 3.2 3.8 2.5 Self-reported 3.5 3.5 2.5 Self-reported and 3.8 3.5 2.5 functionally constipated Not constipated subjects 3.5 3.5 2.2 National average (a) 2.6 3.3 1.1 Recommended (b) 4-9 4-7 2-3 (a)Calculated weighted average number of serves for males from the 1995 National Nutrition Survey.
If there is no mechanical bowel obstruction, evacuation of the impaction can be accomplished with oral polyethylene glycol (eg, GoLytely
) until clear (up to 8 liters or more may be required for complete evacuation).
If the constipation does not respond, then a liquid osmotic agent (a medication that brings extra water into the bowel) -- GoLYTELY
[R] -- may need to be administered under the direction of a physician.
4-L PEG-ELS (GoLytely
), demonstrating increased patient satisfaction and tolerability in the PEG-3350 group while producing similar rates of high-quality bowel preparation (15-17).
Alternatives to this approach include 1 gallon of GoLYTELY
laxative solution or Gatorade and magnesium citrate.
Mylan received final approval for its abbreviated new drug application for polyethylene glycol 3350 and electrolytes for oral solution, a generic version of Braintree Laboratories' GoLytely
This involves cleaning out your bowel the night before the test with either a prep solution such as "Golytely
" or pills.