The intestine was short, with the intestinal epithelium presenting a simple type with a prismatic and cylindrical aspect and a large amount of goblet cells
. These cells were strongly stained by PAS and AB, with neutral and acidic mucopolysaccharides, respectively.
There are three major epithelial cell types in the airways: ciliated cells, Clara cells, and goblet cells
. Ciliated epithelium participates in the mucociliary clearance and expresses P -tubulin on the surface (Tompkins et al.
were counted within the same measurement.
The ileum (harvested just proximal to the ileocecal junction) was processed, sectioned (3 [micro]m), and stained as previously described , and intestinal goblet cell
hyperplasia was quantified as percent villi area covered by Periodic Acid-Schiff (PAS) stain as previously described .
Siggers et al., "Intestinal epithelial Toll-like receptor 4 regulates goblet cell
development and is required for necrotizing enterocolitis in mice," Gastroenterology, vol.
The purpose of this study was to determine whether transgenic overexpression of adiponectin could affect allergic airways responses, including goblet cell
A reduced number of goblet cells
, often with reduced staining.
The mitochondria present in the microvilli of the goblet cell
cavity would be related to active transport mechanisms of K+ ions, realised by these cells (Anderson and Harvey, 1966; Harvey et al., 1983; Moffett et al., 1995).
The natural disease (6) and the experimental infection (1) showed increased activity of goblet cells
(GC) and infiltration of polymorphonuclear neutrophils (PMN) in the nasopharynx and nostrils.
(A) The model group with microvilli sloughing and mitochondria stretching, marked with 1 and 2 respectively; (B) Blank group with normal goblet cells
and intestinal villi, marked with 3 and 4 respectively; (C) Positive drug group with microvilli shortening and membrane of goblet cells
damaged, marked with 5 and 6 respectively; D and E were for CK group and TP group with integral microvilli, marked with 7 and 8, normal cell-cell junction and nuclear membrane, marked with 9 and 10, respectively.
Although no obvious gross pathologic changes were attributed to the nematode, histologic changes of bronchial epithelial hyperplasia and goblet cell
metaplasia, consistent with chronic airway irritation were found in the lungs associated with Diplotriaena eggs.
Table V.- Effect of dietary MOS on villus height, crypt depth and goblet cells
count of broiler birds during finisher phase.