Goodpasture's syndrome

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Goodpasture's syndrome

[′gu̇d‚pas·chərz ‚sin‚drōm]
(medicine)
A complex of symptoms associated with acute glomerulonephritis and pulmonary hemorrhage.
References in periodicals archive ?
But in summer 2007, Marshall Dannen became critically ill with an autoimmune disorder called Goodpasture syndrome, which caused both of his kidneys to fail.
5) Among c-ANCA positive vasculitis such as Goodpasture syndrome, microscopic polyangiitis and Church-Strauss syndrome, (5) WG can be differentiated by biopsy and PR3-ANCA positivity.
Lung biopsy also helps to rule out the other causes of DAH, such as Goodpasture syndrome, Wegener's granulomatosis, systemic lupus erythematosus, and Henoch-Schonlein purpura.
Goodpasture syndrome (anti-glomerular basement membrane antibody syndrome) may present with DAH with or without associated capillaritis, and Wegener granulomatosis may occasionally present with a primary pattern of hemorrhage and capillaritis.
The work may also inform research on Alport syndrome, an inherited condition related to collagen IV that involves loss of kidney function, and Goodpasture syndrome, a rare autoimmune disease.
But now, the 34-year-old, of Porth, Rhondda, who has suffered from Goodpasture syndrome for three years, couldn't be happier.
Discuss the pathophysiology, manifestations, diagnosis, and collaborative management of patients with Goodpasture syndrome.
Describe the pathophysiology of Goodpasture syndrome.
Goodpasture syndrome is a rare disease that can affect the lungs and kidneys.
The most common causes are Goodpasture syndrome, vasculitides such as Wegener granulomatosis and microscopic polyangiitis, and connective tissue diseases, including systemic lupus erythematosus.