Arthrogryposis

(redirected from Gordon Syndrome)
Also found in: Dictionary, Medical.
Related to Gordon Syndrome: Gitelman syndrome, Pseudohypoaldosteronism

arthrogryposis

[‚är·thrō‚grī′pō·səs]
(medicine)
Permanent fixation of a joint in a flexed position.

Arthrogryposis

 

a congenital disease manifested in flexure (contracture) of the joints of the extremities as a result of atrophy of the muscles and replacement of muscle fibers by fatty tissue. In arthrogryposis the upper extremities are pressed to the torso and the elbow joints are unbent; the wrists and fingers are bent and adducted, resembling the talons of a predatory bird. The lower extremities are bent and abducted at the hip joints and unbent at the knees. The feet are deformed (clubfoot). The treatment is orthopedic—corrective splints, operations, and exercises. The earlier the treatment, the better the results.

REFERENCE

Fridland, M. O. Ortopediia, 5th ed. Moscow, 1954.
References in periodicals archive ?
It presents with hypokalaemia, metabolic alkalosis, salt-sensitive hypertension, suppression of plasma renin activity(PRA) and aldosterone secretion.12 Gordon syndrome also known as pseudohypoaldosteronism type II is caused by mutations in any of the four genes; WNK1, WNK4, CUL3 and KLHL3 which are the regulators of the thiazide sensitive Na+- Cl- co transporter.
None of the patients had Liddle syndrome, apparent mineral ocorticoid excess and Gordon syndrome.
INTRODUCTION: Gordon Syndrome has been indexed as a rare disease in the database of NORD (National Organization for rare diseases), [1] and also in Genetic and rare disease Information center.
Gordon Syndrome as seen in present case is a very rare congenital syndrome, manifesting with distal contractures and deformities of multiple joints and cleft palate.