Dermatomyositis

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Related to Gottron's papules: dermatomyositis, shawl sign, heliotrope rash, Gottron's sign

dermatomyositis

[dər¦mad·ō‚mī·ə′sīd·əs]
(medicine)
An inflammatory reaction of unknown cause involving degenerative changes of skin and muscle.

Dermatomyositis

 

a systemic disease chiefly involving the skin, muscles, and nerves.

Dermatomyositis was first described by the German physician E. Wagner and (independently) by the German physician H. Unverricht in 1887 and called acute progressive poliomyositis. In 1891, Unverricht suggested the name “dermatomyositis.” The disease has been little studied, and there is no consensus regarding its origin and development. Dermatomyositis may occur in acute or chronic form; in the latter there are intervals of varying duration (remissions) between exacerbations. The manifestations are extremely variable. The commonest are muscular pains, tension in some muscle groups (especially on movement), reddening of certain parts of the skin (most often on the face near the eyes, cheeks , and nose), peeling, and dilatation of blood vessels in the skin (telangiectasia). Hormonal preparations, antibiotics, antimalarial agents, antihistamines and desensitizing preparations, and vitamins are used in treatment. Dermatomyositis patients should be kept under clinical observation.

G. IA. SHARAPOVA and I. N. VEDROVA

References in periodicals archive ?
A physical examination demonstrated a body temperature of 37.7[degrees]C, mild muscular weakness of the proximal lower limbs, edematous hands, and cutaneous manifestations including a heliotrope rash, Gottron's papules, mechanic's hands, palmar papules, and an erythematous rash on his face and back; in particular, ulcerative and erosive erythema was visible on his elbows (Figures 1 and 2).
For adults, it is not uncommon to have plaques over the knuckles as opposed to the classic Gottron's papules (FIGURE 3).
Sontheimer has proposed a more inclusive classification system for identifying cutaneous manifestations of DM that includes not only the hallmark skin changes associated with DM (Gottron's papules, heliotrope rash, and characteristically distributed macular erythemas), but also minor cutaneous events that can provide diagnostic clues.
Vleugels emphasized that it's important not to miss a more subtle, less violaceous heliotrope eruption, especially in lighter-skinned patients; similarly, Gottron's papules are not always papular and limited to the knuckle pads, but can be more macular and linear, with psoriasiform scaling.
Sontheimer has proposed a more inclusive classification system for identifying cutaneous manifestations of DM that includes both the hallmark skin changes associated with DM (Gottron's papules, heliotrope rash, and characteristically distributed macular erythemas), and minor cutaneous events that can provide diagnostic clues (see box).