Graafian follicle


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Related to Graafian follicle: ovarian follicle, ovulation, corpus luteum

Graafian follicle

a fluid-filled vesicle in the mammalian ovary containing a developing egg cell

Graafian Follicle

 

(named after R. de Graaf), a mul-tilayered saclike follicle that develops in the cortical layer of the ovary of mammals, including humans, under the influence of the follicle-stimulating hormone. The wall of the Graafian follicle consists of an external layer of connective tissue, under which is the multilayered follicular epithelium lining the Graafian follicle cavity, which is filled with a serous liquid. The epithelium forms a process into the Graafian follicle cavity (cumulus oophorus), in which the ovum is located, and provides it with nutrients. The developing follicle produces the hormone estrogen, which prepares the sexual ducts to receive the egg after ovulation, that is, its release from the Graafian follicle and the ovary. The ovulated egg enters the oviduct, where it can join with a spermatozoon and be fertilized. In animals that bear many young at once, several Graafian follicles grow and mature simultaneously.

D. A. POTEMKINA

Graafian follicle

[′gräf·ē·ən ′fäl·ə·kəl]
(histology)
The mature mammalian ovum with its surrounding epithelial cells.
References in periodicals archive ?
The total number of normal and degenerated follicles at different follicular stages: A One-Way ANOVA was conducted to explore the impact of cyclophosphamide and NSO on the total distribution of normal and degenerated primary secondary and Graafian follicles after 5 days of exposure.
Follicles up to 15 mm diameter were considered as developing and beyond 15mm were considered as graafian follicles.
Materials deposited between the cumulus cells of Graafian follicles in gonadotropin-treated mouse ovaries were stained with colloidal iron.
Furthermore, our previous study revealed no alteration in the volumeof ovary,unilaminarprimary follicles, multilaminar primary follicles, secondary follicles, and graafian follicles in the experimental groups (9).
sativa stimulated release on LH that caused luteinization of the Graafian follicles in the ovaries, resulting in increased concentrations of serum progesterone.
The histological analysis of ovaries showed the presence of newly formed corpora lutea or Graafian follicles in all the treated rats indicating that these rats were in estrous or in proestrous phases of the estrous cycle, respectively.
Capacity of immunologically purified FSH to stimulate cyclic AMP accumulation and steroidogenesis in Graafian follicles and to induce ovum maturation and ovulation in the rat.