Granulations


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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Granulations

 

in medicine, the moist, bright red tissue with granular surface that develops during the healing of wounds of inflammatory foci.

Granulations are rich in blood vessels and young connective-tissue cells, which rapidly proliferate and replace the destroyed section of tissue. When there is excessive formation of granulations, such as in the area surrounding a fistula (so-called proud flesh), healing is impaired. Granulations of this sort are removed surgically.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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For realizing the study of the pieces porosity variations dependent on the powder granulation have been used powders: 56 [micro]m, 63 [micro]m, 100 [micro]m, and >160 [micro]m.
One key reason is that Starch 1500 performs multiple functions within a wet granulation formulation: as a binder, disintegrant, filler and lubricant, eliminating the need for a multitude of costly excipients and additional processing steps.
These granulations are primarily located in the vicinity of dural venous sinuses and most are close to the sagittal sinus.
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