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A discrete nodular lesion of inflammatory tissue in which granulation is significant.



a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.

References in periodicals archive ?
Lesions like leprosy, erythema nodosum leprosum, trichoepithelioma, and metastatic carcinoma were more common in males, whereas Prurigo Nodularis and granuloma annulare were more common in females.
Yun JH, Lee JY Kim MK, et al: Clinical and pathological features of generalized granuloma annulare with their correlation: a retrospective multicenter study in Korea.
The affected area may closely resemble other dermatologic conditions that can manifest as round patches or plaques such as pityriasis rosea, nummular eczema, granuloma annulare, psoriasis, tinea versicolor, and annular contact dermatitis.
Annular elastolytic granuloma is a variant of granuloma annulare that occurs on skin that has been exposed to the sun.
Granuloma annulare is often self-limiting and resolves within 2 years, although recurrence is possible.
Five cases of granuloma annulare occurring at the site of prior herpes zoster were identified between 2006 and 2011 and included in this study.
He and his colleagues found that adults with granuloma annulare are four times more likely to develop dyslipidemia than those without the inflammatory dermatosis.
When in doubt, biopsy to differentiate from lichen planus, molluscum contagiosum, flat warts, granuloma annulare, and lichen spinulosus.
The histopathologic appearance was similar to the diffuse form of granuloma annulare except for the presence of the pseudorosettes.
Commonly herpes zoster is the initial disease on which granuloma annulare, sarcoidosis appear.
Granuloma annulare is characterized by red or skin-colored plaques in annular and rope-like patterns with central clearing and nonscaly borders.
Iron staining may help distinguish KS from similar-appearing interstitial granuloma annulare lesions that lack iron.