Samuel David Gross

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Gross, Samuel David,

1805–84, American surgeon, b. near Easton, Pa., M.D. Jefferson Medical College, Philadelphia, 1828. He taught at the medical colleges of several universities and at Jefferson from 1856. He made outstanding contributions to his profession as teacher of pathological anatomy and surgery; as inventor of surgical instruments and techniques; as author of Elements of Pathological Anatomy (1839), A System of Surgery (1859), and other works; and as a founder of the American Medical Association.


See his autobiography (1887).

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Gross, Samuel David

(1805–84) surgeon, author; born near Easton, Pa. After taking his M.D. from Jefferson Medical College (Philadelphia), he set up practice in Philadelphia; he translated and wrote several important works on anatomy and surgery. He went on to teach at Cincinnati Medical College and the University of Louisville before returning to Jefferson Medical College as professor of surgery (1856–82). He had an international reputation as both a teacher and practitioner of surgery, and he continued to be a prolific author; several of his texts were classics, among them Elements of Pathological Anatomy (1839) and System of Surgery, Pathological, Diagnostic, Therapeutic and Operative (1859). His specialties included operations for bladder stone and intestinal wounds; he invented new techniques and instruments. He was one of the founders and most influential members of the American Medical Association (1847). Thomas Eakins portrayed him in a famous painting, The Clinic of Dr. Gross (1875).
The Cambridge Dictionary of American Biography, by John S. Bowman. Copyright © Cambridge University Press 1995. Reproduced with permission.
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It may be given for a limited time as adjuvant therapy, when there is no gross disease to treat.
Radiotherapy 8 Gy in 1 fraction was administered using 6MV (mega voltage) Primus Linear Accelerator with 2-2.5 cm margin around the gross disease at the Oncology department, CMH Rawalpindi.
The gross tumor volume (GTV) was defined as all gross disease seen on the planning scans.
The patient was then treated with image-guided radiotherapy (IGRT) at the dose of 54 Gy in the surgical bed and in regions of gross disease (bilateral paravertebral between T10 and S1).
(51) disease 3 patients 2013 who received postoperative RT Liu Gross disease 44% 10 months et al.
R2: gross disease, macroscopic/visible tissue left behind.
For women who do not desire fertility, this includes total hysterectomy, bilateral salpingooophorectomy and removal of all gross disease. Comprehensive nodal dissection is not indicated except when necessary for complete cytoreduction.
Since these studies were published between 1983 to 2012, the criteria for optimal cytoreduction varied from <2.5cm to no gross disease, we tabulated them according to the criteria used to see the rate of optimal secondary cytoreduction and their OS [Table 5].
All but one patient (who was given adjuvant CRT after surgical resection) had gross disease present at the start of treatment.
Postoperatively the patient did well and appears to be free of gross disease after the surgical resection.
It was therefore concluded that a dose-response existed for subclinical and gross MCC, with doses of ?50Gy for subclinical disease, and greater than 55Gy for gross disease to be considered.
"My own view, in terms of what we are now doing, which is treating gross disease, is that gross disease will become minimal disease - sub-clinical disease treated by new technologies."
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