Samuel David Gross

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Gross, Samuel David,

1805–84, American surgeon, b. near Easton, Pa., M.D. Jefferson Medical College, Philadelphia, 1828. He taught at the medical colleges of several universities and at Jefferson from 1856. He made outstanding contributions to his profession as teacher of pathological anatomy and surgery; as inventor of surgical instruments and techniques; as author of Elements of Pathological Anatomy (1839), A System of Surgery (1859), and other works; and as a founder of the American Medical Association.


See his autobiography (1887).

Gross, Samuel David

(1805–84) surgeon, author; born near Easton, Pa. After taking his M.D. from Jefferson Medical College (Philadelphia), he set up practice in Philadelphia; he translated and wrote several important works on anatomy and surgery. He went on to teach at Cincinnati Medical College and the University of Louisville before returning to Jefferson Medical College as professor of surgery (1856–82). He had an international reputation as both a teacher and practitioner of surgery, and he continued to be a prolific author; several of his texts were classics, among them Elements of Pathological Anatomy (1839) and System of Surgery, Pathological, Diagnostic, Therapeutic and Operative (1859). His specialties included operations for bladder stone and intestinal wounds; he invented new techniques and instruments. He was one of the founders and most influential members of the American Medical Association (1847). Thomas Eakins portrayed him in a famous painting, The Clinic of Dr. Gross (1875).
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Quad shot radiotherapy was delivered, at the Oncology department CMH Rawalpindi, using two opposing lateral beams, target volume included the gross disease with a 2 cm margin all around.
R2: gross disease, macroscopic/visible tissue left behind.
For women who do not desire fertility, this includes total hysterectomy, bilateral salpingooophorectomy and removal of all gross disease.
5cm to no gross disease, we tabulated them according to the criteria used to see the rate of optimal secondary cytoreduction and their OS [Table 5].
Postoperatively the patient did well and appears to be free of gross disease after the surgical resection.
50Gy for subclinical disease, and greater than 55Gy for gross disease to be considered.
My own view, in terms of what we are now doing, which is treating gross disease, is that gross disease will become minimal disease - sub-clinical disease treated by new technologies.
The concept of surgical debulking put forward by Bristow and coworkere still has merit, and any gross disease should be removed, if feasible.
Since there was no postoperative evidence of gross disease in the nose or paranasal sinuses, we believe that a more radical and aggressive surgical intervention was not warranted in this case.
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