G protein

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G protein

[′jē ‚prō‚tēn]
(cell and molecular biology)
References in periodicals archive ?
12/13]-type G proteins, which leads to activation of small GTP-binding proteins Rho through activation of RhoGEF (RhoGTPase nucleotide exchange factor) (see a review ref.
Comparative genomics of prokaryotic GTP-binding proteins (the Era, Obg, EngA, ThdF (TrmE), YchF and YihA families) and their relationship to eukaryotic GTP-binding proteins (the DRG, ARF, RAB, RAN, RAS and RHO families).
Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins.
The P-loop--a common motif in ATP and GTP-binding proteins Trends Biochem.
In large part, the anti-inflammatory actions of statins result from the depletion of two biologically important cholesterol pathway intermediates, farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP), which are required for posttranslational modification of small GTP-binding proteins (small GTPases) such as Ras (FPP) or Rac and Rho (GGPP) (Figure 3).
Purification of heterotrimeric GTP-binding proteins from brain: identification of a novel form of Go.
To better understand the link between MIH receptor occupancy and Y-organ cAMP levels, we have assessed the presence of GTP-binding proteins (G-proteins) in Y-organs of the blue crab (Callinectes sapidus).
Despite the dramatic changes induced by EPEC in the cytoskeleton, there appears to be little involvement of the Rho family of small GTP-binding proteins normally involved in cytoskeletal rearrangements (29).
Chadi et a1 (22), reported that compound 48/80 activated mast cell phospholipase D (PLD) via heterotrimeric GTP-binding proteins (22).
In previous studies, we and others have demonstrated that nitric oxide is also important in regulating motility in sea urchin sperm, and we have found further that this process is likely to be dependent on the activity of GTP-binding proteins (11-13).
coli belong to a group of bacterial toxins that modify Rho, a subfamily of small GTP-binding proteins that are regulators of the actin cytoskeleton (28,29).