Screening was performed in three steps; first, Phenylalanine (Phe) levels were determined using the Guthrie test
that is an enzymatic colorimetric method (PKU kit-Misagh Talashgaran, Iran).
South Yorkshire Police, who launched a cold case review into the disappearance, organised for DNA to be extracted from a heel prick blood test, called a Guthrie test
, which was taken by a hospital when Ben was born.
All newborns are given the Guthrie test
which picks up conditions affecting about one in 40,000 babies.
The inquiry team homed in on the missing girl's Guthrie Test
- a blood sample taken shortly after birth from all babies.
He added: "Phenylketonuria (PKU) is tested for in every new born baby in Britain via the 'Guthrie Test
While quite likely, we could have devised a list far greater than 7 Wonders that just encompasses medical breakthroughs for those with disabilities, EP ranks the following two as highly significant because of their historical qualities, their far-reaching impact, and the fact that they represent discoveries that sought to prevent a disabling condition altogether or lessen its impact, the Guthrie test
and the polio vaccine.
For that purpose, 3.2-mm (1/8-inch) spots were punched from Guthrie test
cards by an automated punching device and transferred to a 96-well microtiter plate.
They often ask doctors whether this Guthrie test
is really necessary.
The Guthrie test
measures the amount of phenylalanine in the blood.
after Vick 1991 m INITIATIVE: Mulholland Every baby in Scotland is given the Guthrie test
. A card like the one above proved crucial