heavy chain

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heavy chain

[′hev·ē ′chān]
(immunology)
The heavier of the two types of polypeptide chains occurring in immunoglobulin molecules, its molecular weight range being 50,000-70,000. Also known as A chain; H chain.
References in periodicals archive ?
NMR [sup.1]H (DMSO) [delta] (ppm): 1.23 (t, J = 6.9 Hz, 3H, C[H.sub.3]); 4.20 (q, J = 6.9 Hz, 2H, CH2); 5.64 (d, J = 13.2 Hz, 1H, H-chain); 7.22 (t, J = 7.8 Hz, 1H, Ar-H); 7.29 (d, J = 12.6 Hz, 1H, H-chain); 7.42 (t, J = 8.1 Hz, 1H, Ar-H); 7.46 (d, J = 7.5 Hz, 1H, Ar-H); 7.77 (d, J = 7.5 Hz, 1H, Ar-H); 13.02 (s, 1H, NH).
NMR [sup.1]H (DMSO) [delta] (ppm): 1.16 (t, J = 7.6 Hz, 3H, C[H.sub.3]); 1.25 (t, J = 8.0 Hz, 3H, C[H.sub.3]); 4.02 (q, J = 7.2 Hz, 2H, C[H.sub.2]); 4.26 (q, J = 8.0 Hz, 2H, C[H.sub.2]); 5.79 (d, J = 12.4 Hz, 1H, H-chain); 7.27 (t, J = 7.6 Hz, 1H, Ar-H); 7.44-7.54 (m, 3H, Ar-H, H-chain); 7.83 (d, J = 7.6 Hz, 1H, Ar-H).