antagonist

(redirected from H2 receptor antagonist)
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antagonist

1. any muscle that opposes the action of another
2. a drug that counteracts the effects of another drug

antagonist

[an′tag·ə‚nist]
(biochemistry)
A molecule that bears sufficient structural similarity to a second molecule to compete with that molecule for binding sites on a third molecule.
(pharmacology)
A drug or other chemical substance capable of reducing the physiological activity of another chemical substance; refers especially to a drug that opposes the action of a drug or other chemical substance on the nervous system by combining with and blocking the nerve receptor.
(physiology)
A muscle that contracts with, and limits the action of, another muscle, called an agonist, with which it is paired.
References in periodicals archive ?
In the present study, highest seroprevalence of H.pylori was seen in diabetic patients on oral hypoglycemic drugs (70) as compared to patients on insulin therapy, on NSAIDS and on H2 receptor antagonist Corroborating our results Ojetti et al observed that there is increase in insulin requirement in H.
Another H2 receptor agonist, dimaprit, improved extinction of aversive memory, while the H2 receptor antagonist, RA, impaired this memory (33,34).
The lack of effect of the H1 and H2 receptor antagonists was surprising in view of our previous findings.
Increasing use of antacids, H2 receptor antagonists and proton pump inhibitors in primary care (19) may also contribute to the reduction of the incidence of gastrointestinal bleeding in patients with spinal cord injuries.
Omeprazole is a much more potent inhibitor of gastric acid secretion than H2 receptor antagonists. Therefore it is indicated for the treatment of severe gastrointestinal reflux disease and active duodenal ulcers unresponsive to H2 receptor antagonists and hypersecretory gastrointestinal conditions (e.g., Zollinger-Ellison syndrome, multiple endocrine adenomas, systemic mastocytosis) (McEvoy, 1996).
They compared outcomes of acid suppression therapies including PPI and histamine H2 receptor antagonists (H2 blockers) for all-cause mortality rates.
Pharmaceutical agents that are used to prevent complications and reduce morbidity in patients with GERD include antacids, H2 receptor antagonists, proton pump inhibitors (PPIs), and prokinetic agents.