Clinical Acronyms Atypical glandular cells AGC Atypical glandular cells not otherwise specified AGC-NOS Adenocarcinoma in situ AIS Atypical squamous cells ASC Atypical squamous cells: cannot exclude high-grade ASC-H Atypical squamous cells of undetermined significance ASC-US Cervical intraepithelial neoplasia CIN High-grade squamous epithelial neoplasia HGSIL
Human papillomavirus HPV Low-grade squamous intraepithelial lesion LGSIL
All the HGSILs
in this study occurred in women younger than 30 years of age, which is much lower than the usual age distribution for high-grade lesions (around 35 - 40 years of age).
Follow-up colposcopies performed post partum indicated no change in the grade of lesions among 63% of the patients with HGSILs
, 64% of patients with LGSILs, and 76% of the patients with ASCUS.
The descriptor ASCUS refers to cells that are more abnormal than cells seen in reactive or inflammatory lesions, but do not fulfill all the criteria for LGSIL or HGSIL
(*) LGSIL indicates low-grade squamous intraepithelial lesion; HGSIL
, high-grade squamous intraepithelial lesion; and TN score, expression of tenascin in the basement membrane.
Normal 4 11 1 LGSIL 0 11 1 HGSIL
2 5 12 Total 6 27 14
To evaluate the reliability of using repeat cervical smears to separate patients with high-grade SIL (HGSIL
) from those with low-grade SIL (LGSIL), calculations were repeated, with both repeat cytologic and biopsy LGSIL results included in the "negative" group.
(%) LGSIL 20 (66.7) 28 (59.6) HGSIL
10 (33.3) 19 (40.4) Pretreatment NSAID, no.