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Hand-Schüller-Christian disease (redirected from Hand-Schuller-Christian disease)
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Hand-Schüller-Christian disease[¦hänt ¦shil·ər ′kris·chən di‚zēz]
A childhood syndrome characterized by exopthalmos, diabetes insipidus, and softened or punched-out areas in the bones.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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All these findings are consistent with Hand-schuller-Christian disease
DISCUSSION: Histiocytosis X is a clonal proliferation disease of langerhan's cells that express an immunophenotype positive for S100 and CD1a (7) Hand-schuller-christian disease
is a well described entity which has appeared sporadically till 1935.the cases have been reported from the western literature but authentic case reports from India are few (8,9).
 In 1868, Paul Langerhans discovered epidermal dendritic cells and the conditions which were characterized by these cells were subsequently called different names like Hand-Schuller-Christian disease
, Letterer-Siwe disease, and eosinophilic granuloma.