Hantzsch synthesis

Hantzsch synthesis

[′hänsh ‚sin·thə·səs]
(organic chemistry)
The reaction whereby a pyrrole compound is formed when a β-ketoester, chloroacetone, and a primary amine condense.
References in periodicals archive ?
Thus, we decided to investigate the Hantzsch synthesis under these conditions.
The Hantzsch synthesis, discovered in the 19th century, has been significant for over a hundred years, and its use will likely continue well into the 21st century.