haplotype

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haplotype

[′hap·lə‚tīp]
(genetics)
A set of alleles of closely linked loci on a chromosome that tend to be inherited together; commonly used in reference to the linked genes of the major histocompatibility complex.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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In the SREBF1 to GH (S-G) segment, there are 3 x 5 x 7 x 2 x 3 = 630 possible haplotypes on each paternal or maternal chromosome.
The association between T1D and specific HLA class II alleles, haplotypes, and genotypes was assessed using an odds ratio (Table 3).
Based on traditional AS-PCR, this paper has developed a simple, fast, and cost-effective strategy for analyzing the haplotypes of unrestricted PCR products.
They first showed that they could identify centromeric haplotypes, or "cenhaps," in Drosophila fruit flies.
Twenty-seven polymorphism sites were observed within the Agu population, demonstrating five different haplotypes (type 1-type 5).
A Chi-square test for differences in haplotype frequencies across the four sample sites was significant ([chi square] = 67.20, P = 0.003) indicating that haplotypes are unevenly distributed among the four sampling locations (Hudson et al., 1992).
Conservationists hope the identification of a fifth haplotype will support efforts to restore squirrel numbers in the region.
A total of 67 distinct haplotypes were observed when all 9 genetic markers were considered (online Technical Appendix 1 Table 1), of which 53 were unequivocal and 14 corresponded to samples in which 1 or 2 of the markers failed to amplify.
The comparison of luciferase activities according to PTGS2 haplotypes was performed with the GraphPad Prism 5.0 software (GraphPad Software, USA), using the non-parametric Mann-Whitney U-test for comparison of two groups, or the Kruskal-Wallis test with Dunn's posttest for comparison of multiple groups.