In the SREBF1 to GH (S-G) segment, there are 3 x 5 x 7 x 2 x 3 = 630 possible haplotypes
on each paternal or maternal chromosome.
The association between T1D and specific HLA class II alleles, haplotypes
, and genotypes was assessed using an odds ratio (Table 3).
Based on traditional AS-PCR, this paper has developed a simple, fast, and cost-effective strategy for analyzing the haplotypes
of unrestricted PCR products.
Although WS and JK were relatively close, JK found six haplotypes
, while WS found only one.
They first showed that they could identify centromeric haplotypes
, or "cenhaps," in Drosophila fruit flies.
Twenty-seven polymorphism sites were observed within the Agu population, demonstrating five different haplotypes
(type 1-type 5).
A Chi-square test for differences in haplotype
frequencies across the four sample sites was significant ([chi square] = 67.20, P = 0.003) indicating that haplotypes
are unevenly distributed among the four sampling locations (Hudson et al., 1992).
Conservationists hope the identification of a fifth haplotype
will support efforts to restore squirrel numbers in the region.
A total of 67 distinct haplotypes
were observed when all 9 genetic markers were considered (online Technical Appendix 1 Table 1), of which 53 were unequivocal and 14 corresponded to samples in which 1 or 2 of the markers failed to amplify.
from Korea (H34-H49) and 2 from the USA (H50-H51) were novel.
The comparison of luciferase activities according to PTGS2 haplotypes
was performed with the GraphPad Prism 5.0 software (GraphPad Software, USA), using the non-parametric Mann-Whitney U-test for comparison of two groups, or the Kruskal-Wallis test with Dunn's posttest for comparison of multiple groups.