hapten

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Related to Haptens: Epitopes

hapten

(immunology)
An incomplete antigen that cannot induce antibody formation by itself but can do so by coupling with a larger carrier molecule.
References in periodicals archive ?
Patch tests were performed with 40 haptens from the European Baseline Series (Euromedical s.r.l., Chemo-technique Diagnostics, Italy).
Subtoxic concentrations of allergenic haptens induce LC migration and maturation in a human organotypic skin explant culture model: a novel method for identifying potential contact allergens.
The name adjuvants, one of the conjugates used to increase the immunity of the haptens, is derived from the Latin word adjuvare, which means help or healing (12).
In vitro human T cell sensitization to haptens by monocyte-derived dendritic cells.
The potential scope of [sup.68]Ga-based imaging agents is rather extensive including ligands specifically targeting receptors, enzymes, and antigens; hapten and effector molecules involved in pretargeted imaging; small molecules with biological function to monitor glycolysis, hypoxia, cell proliferation, and angiogenesis; nontargeting particles of various sizes for imaging of ventilation and perfusion [4].
This model states that covalent binding of a reactive drug (hapten) or a reactive metabolite of a chemically inert drug (prohapten) to a high molecular weight protein turns it immunogenic following presentation by HLA molecules [28, 29].
Because all our subjects in the 160 mg/kg/day ip/sc agmatine treated group and 80 mg/kg/day sc agmatine treated group developed similar skin lesions, we claim that agmatine act as a potent hapten in cutaneous/subcutaneous tissue.
The haptens (European baseline, dental screening, and metal series) were provided by Chemotechnique Diagnostics (Vellinge, Sweden).
Allergy causing foods contain chemical substances (typically proteins, sometimes with small molecules called haptens) that elicit specific immunologic reactions causing hypersensitivity reactions if eaten uncooked, cooked or sometimes even after they have undergone digestion (Sicherer and Sampson, 2006; Waserman and Watson, 2011; Sampson et al., 2014).
Similar to Janda's antiheroin vaccine, haptens are bound to a protein carrier, spurring the immune system to create high levels of antibody to bind heroin and its metabolites in the blood and prevent it from crossing the blood-brain barrier.
(1) ACD is generally induced by small compounds called haptens (less than 500 daltons of molecular weight).