Patch tests were performed with 40 haptens
from the European Baseline Series (Euromedical s.r.l., Chemo-technique Diagnostics, Italy).
Subtoxic concentrations of allergenic haptens
induce LC migration and maturation in a human organotypic skin explant culture model: a novel method for identifying potential contact allergens.
The name adjuvants, one of the conjugates used to increase the immunity of the haptens
, is derived from the Latin word adjuvare, which means help or healing (12).
In vitro human T cell sensitization to haptens
by monocyte-derived dendritic cells.
The potential scope of [sup.68]Ga-based imaging agents is rather extensive including ligands specifically targeting receptors, enzymes, and antigens; hapten
and effector molecules involved in pretargeted imaging; small molecules with biological function to monitor glycolysis, hypoxia, cell proliferation, and angiogenesis; nontargeting particles of various sizes for imaging of ventilation and perfusion .
This model states that covalent binding of a reactive drug (hapten
) or a reactive metabolite of a chemically inert drug (prohapten) to a high molecular weight protein turns it immunogenic following presentation by HLA molecules [28, 29].
Because all our subjects in the 160 mg/kg/day ip/sc agmatine treated group and 80 mg/kg/day sc agmatine treated group developed similar skin lesions, we claim that agmatine act as a potent hapten
in cutaneous/subcutaneous tissue.
The effect of haptens
on protein-carrier immunogenicity.
(European baseline, dental screening, and metal series) were provided by Chemotechnique Diagnostics (Vellinge, Sweden).
Allergy causing foods contain chemical substances (typically proteins, sometimes with small molecules called haptens
) that elicit specific immunologic reactions causing hypersensitivity reactions if eaten uncooked, cooked or sometimes even after they have undergone digestion (Sicherer and Sampson, 2006; Waserman and Watson, 2011; Sampson et al., 2014).
Similar to Janda's antiheroin vaccine, haptens
are bound to a protein carrier, spurring the immune system to create high levels of antibody to bind heroin and its metabolites in the blood and prevent it from crossing the blood-brain barrier.
(1) ACD is generally induced by small compounds called haptens
(less than 500 daltons of molecular weight).