Ichthyosis

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ichthyosis

[‚ik·thē′ō·səs]
(medicine)
A congenital skin disease characterized by dryness and scales, especially on the extensor surfaces of the extremities.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Ichthyosis

 

fish skin disease, xeroderma, a skin disease characterized by sharply increased keratogenesis and retarded keratolysis.

Incidence of ichthyosis is a familial condition in half the cases and hereditary in 25 percent. It appears in early childhood (most often around age three), intensifies at puberty, and lasts throughout life. It is expressed in dryness of the skin and the accumulation of horny masses on the skin’s surface, in the form of scales or of massive horny plates that resemble fish scales. The excretion of oil and perspiration decreases sharply. The affection spreads over the entire skin surface, except at joint folds, axillae, and inguinal folds. On the face and scalp, ichthyosis appears in the form of furfuraceous desquamation. The condition of the skin improves in the summertime as a result of increased excretion of oil and sweat. Ichthyosis is treated with hot baths containing soda or table salt, followed by lubrication of the skin with emollient creams. Cod-liver oil and vitamins may be taken internally (in particular vitamin A). In the summer, prolonged sojourns in the south can be helpful (sea bathing).

I. N. VEDROVA

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Mui Thomas is thought to be one of the oldest people known with Harlequin ichthyosis, as children with the condition often die, as they are vulnerable to infection as their skin cracks.
Based on these findings, the newborn was diagnosed with "harlequin ichthyosis" and admitted to the neonatal intensive care unit for treatment and monitoring.
Keywords: Harlequin ichthyosis, autosomal dominant.
The skin abnormalities associated with harlequin ichthyosis disrupt the skins protective barrier, making it difficult to control water loss, regulate their body temperature, and fight infections.
The 3 major types of autosomal recessive congenital ichthyosis are Harlequin ichthyosis, lamellar ichthyosis, and congenital ichthyosiform erythroderma.
Harlequin ichthyosis is an autosomal recessive disease.
How dare I be miserable about my trivial travails when other poor souls are dealing with stuff like Harlequin ichthyosis? Get a grip, son.
Harlequin ichthyosis is a severe and usually lethal form of congenital ichthyosis, caused by a mutation in the ABCA12 gene.
It seems that the mutated ABCA 12 gene in harlequin ichthyosis has something to do with the production of the lamellar granules in the upper layers of the skin.
Moving documentary profiling Lara Bowen and Hannah Betts (above) who suffer from the rare genetic skin disorder harlequin ichthyosis.
The seven-year-old suffers from Harlequin ichthyosis which affects just seven children across the UK.
Five-year-old Ellie Luther, from South Shields, is one of just a handful of children with Harlequin ichthyosis, a condition so extreme doctors have difficulty diagnosing it.