Independent samples t-test was used to detect any significant difference between the experimental and control groups by comparing mean numbers of epithelioreticular cells and the size and number of Hassall's corpuscles in the medulla of thymus.
Although, no considerable difference was encountered between the experimental and control groups regarding the number of Hassall's corpuscles, their diameter was considerably larger in the group exposed to retinoic acid (p=0.004) (table).
The length and the size of Hassall's corpuscles were also significantly different in the experimental subgroup A2 and control subgroup B2 (table-I).
The expression of TSHR was frequently detected in the Hassall's corpuscles and thymocytes of normal thymic tissues.
In further study, it may get better results if in situ RT-PCR to define the location of the mRNA expression or qRT-PCR after laser-dissection for Hassall's corpuscles or cell fraction/sorting for thymocytes is performed.
The positive stained cells in Hassall's corpuscles (arrows) and in thymocytes (arrowheads) are indicated.
(16.) Gilhus N E, Matre R and Tonder O.: Hassall's Corpuscles in the thymus of foetuses, infants and children: immunological and histochemical aspects.
One Hassall's corpuscle of relatively larger size but still in early stages of formation with a single nucleus was seen (Fig.
The first developing Hassall's corpuscle was reported at 13th week by Varga et.
However, two of the specimens from 79 year old specimens showed normally lobulated thymus with reticulocytes and Hassall's corpuscles.
The number of Hassall's corpuscles per low power field was assessed in all the specimens.