Hayflick limit


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Hayflick limit

[′hā‚flik ‚lim·ət]
(physiology)
The finite replicative capacity of normal somatic cells.
References in periodicals archive ?
These results suggested that the Hayflick limit is only applicable to cell line with mass population and that life span of an individual cell is governed by telomere shortening due to oxidative stress.
THE ISOLATION OF HUMAN SENESCENT CELLS BY THEIR INABILITY TO ATTACH TO FIBRONECTIN
For example, one is to find a way to overcome the Hayflick limit on cell reproduction.
Life and death
This culture removes the Hayflick limit [the number of times that a normal cell population will divide until cell division stops] of these cancer cells and allows them to multiply at a phenomenal rate, creating many billions to trillions of identical CTCs/CSCs with no change to their genetics, epigenetics, and phenotype expressions.
Chemosensitivity testing: customizing cancer treatment
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