Hematopoietic Organs

Hematopoietic Organs

 

in animals and man, the organs in which the formed elements of the blood and lymph are produced.

In adult mammals and man, the principal hematopoietic organ is the bone marrow, where the red blood cells (erythrocytes), granular white blood cells (granular leukocytes), blood platelets (thrombocytes), and certain agranular white blood cells (lymphocytes) are formed. It is mostly lymphocytes that are formed in the other hematopoietic organs (that is, the lymph nodes, spleen, and thymus). Granular leukocytes and erythrocytes are formed otherwise in certain mammals only in the spleen. The yolk sac and liver also serve as hematopoietic organs in the mammalian embryo. The kidneys and liver perform the function in the lower vertebrates. In invertebrates, blood cells form directly in the perivisceral fluids and hemolymph.

Intensive proliferation and maturation of hematopoietic and lymphoid cells go on throughout the life of an organism. This compensates for the natural loss of blood cells and lymphocytes, which survive only a few days to a few months. Hematopoiesis is maintained by the stem cells, the element common to all hematopoietic tissues. Stem cells are found primarily in the bone marrow, but they can enter the other hematopoietic organs with the blood. The stem cells develop into erythrocytes, leukocytes, or thrombocytes, depending upon which of the hematopoietic organs they reach.

Hematopoietic organs are made up not only of hematopoietic cells but also of supporting tissue, or stroma. It is largely the interaction of the stroma with the stem cells that determines the type of blood cell production in the given organ. Immunologically active cells (lymphocytes and plasma cells) are also formed in the hematopoietic organs, which are the site of important stages in the influence on the cells of antigens.

A. IA. FRIDENSHTEIN

References in periodicals archive ?
Contract award notice: Supply of drugs of group b of the atc classification (blood and hematopoietic organs) (spain-murcia: Various medicinal products)
Fluoride-induced disorders in hematopoietic organs in mice and in human hematopoietic progenitor cells are known (Machalinska et al.,2002).
Examples of these include: the hematopoietic organs, intestine and gut, reproductive organs, lenses eyes, skin, and thyroid than non-sensitive cells are those that do not grow or reproduce, such as brain and muscle cells in adults.
delivery to the provincial specialist hospital in biala podlaska of various medicinal products, Medicinal products for the cardiovascular system, Medicinal products for the treatment of gastrointestinal disorders, Sex hormones and modulators of the genital system, Medicinal products for the treatment of the nervous system, Antihemorrhagics, Anticoagulants blood, Antimicrobial agents for systemic use, Therapeutic agents for the respiratory system, Medicinal products for blood and hematopoietic organs, Analgesics, Anesthetics, Pharmaceutical products, Diuretics, Mineral supplements, Antimycotics for systemic use, Medicinal products for the musculoskeletal system , Vaccines, Immunoglobulins, Bcg vaccines divided into 69 parts.
supply of medicinal products: Painkillers, Diuretics, Antihemorrhagic agents, For the treatment of the respiratory system, Medicinal products for parenteral nutrition, For the cardiovascular system, For blood and hematopoietic organs, For the nervous system, For treating disorders of the gastrointestinal tract, For the musculoskeletal system skeletal, Antifungal drugs, Mineral, Ophthalmic, Diuretic, Gynecological agents, Antibacterials for systemic use divided into 31 parts
Contract notice: supply of drugs for the blood and for the hematopoietic organs
Tenders are invited for provision of drugs for blood and hematopoietic organs to the foundation of the health management of the hospital of the holy cross and saint paul
Supply of blood medications and hematopoietic organs to the Sanctuary of Sanctuary of the Healthcare Foundation of the Santa Creu and Sant Pau Hospital
17 lots broken down as follows: - - b pharmaceutical specialties with amm: Blood and hematopoietic organs (code atc b) - - c pharmaceutical specialties with amm: Cardiovascular system (code atc c) - - h pharmaceutical specialties with amm: General anti-infectious agents for systemic use (code atc j) - - i pharmaceutical specialties with amm: Antineoplastic and immunomodulating agents (atc code) - - j pharmaceutical specialties with amm: Muscle and skeleton (code atc m) - - k pharmaceutical specialties with amm: Nervous system (code atc n).
Section II and Blood and hematopoietic organs. 1.3.
Contract awarded for pharmaceutical products, blood products, hematopoietic organs and the cardiovascular system, urogenital system drugs and hormones, systematic use of corticosteroids, preparations for the nervous system and sensory organs, preparations respiratory / respiratory system, various medicinal products, infusion solutions, diagnostic utilities
Contract award: contract to supply drugs for blood and hematopoietic organs.

Full browser ?