ASC-101 will potentially transform hematopoietic stem cell transplantation
by accelerating patients' immune system and platelet recovery, reducing opportunistic infections and other co-morbidities, and possibly improving patient survival.
Datamonitor insight into hematopoietic stem cell transplantation
CHAPTER 2 HEMATOPOIETIC STEM CELL TRANSPLANTATION
CB001, its lead cord blood derived stem cell therapy product candidate, is being developed for hematopoietic stem cell transplantation
in patients affected by a variety of cancers.
The FDA previously approved an IND for rhMBL for the prevention and treatment of severe infections in patients with multiple myeloma with low levels of MBL undergoing high-dose chemotherapy and hematopoietic stem cell transplantation
in August 2006.
Malignant infantile osteopetrosis (MIOP) is a rare hereditary disorder of osteoclast function, which can be reversed by hematopoietic stem cell transplantation
Johanna Song, MD, a resident dermatologist at Harvard University, Boston, and her collaborators reported that in their study 25% of patients had permanent alopecia and 16% had psoriasis, noting that late nonmalignant skin effects of hematopoietic stem cell transplantation
(HSCT) have been studied primarily retrospectively, and in adults.
The discovery may also have important implications for hematopoietic stem cell transplantation
since it may lower the risk of graft-versus-host disease, a potentially fatal condition that can occur after hematopoietic stem cell transplants for genetic diseases and blood cancers.
While hematopoietic stem cell transplantation
is currently the only known cure and advancements have been made in treating complications, more can be done to help patients and their families.
The cousin said the boy remains in a hospital because he needs hematopoietic stem cell transplantation
, and his family cannot afford it.
This antigen makes BC8 potentially useful in targeting white blood cells in preparation for hematopoietic stem cell transplantation
in a number of blood cancer indications, including acute myeloid leukemia, chronic myeloid leukemia, acute lymphoblastic leukemia, chronic lymphocytic leukemia, Hodgkin's disease, Non-Hodgkin lymphomas and multiple myeloma, revealed the company.
As ascorbic acid has a major influence on (re)generation of immune cells in vitro, we executed an observational study in which ascorbic acid serum values of patients with hematological malignancies treated with and without hematopoietic stem cell transplantation
were compared with those of healthy volunteers to see if low ascorbic acid levels should be considered of importance regarding immune recovery of these patients," explained authors Mirelle Huijskens and colleagues.