Hemolysins


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Related to Hemolysins: Leukocidins

Hemolysins

 

substances capable of liberating hemoglobin from red blood cells. Upon liberation by hemolysins, the hemoglobin dissolves in the plasma or surrounding fluid and the blood (or the suspension of red blood cells) becomes transparent (laked blood). Hemolysins are the products of the vital activities of many bacteria (for example, staphylococci and streptococci), parasitic worms, insects, scorpions, and some poisonous snakes (lysolecithins). Hemolysins may be present in the blood serum and lyse the body’s own red blood cells (autohemolysis). However, they generally appear after intravenous injection of red blood cells obtained from the same species of animal (isohemolysins) or from another species (heterolysins). The hemolytic properties of these serums, which depend upon the presence of complement (a thermolabile substance needed for the action of heterolysins upon red blood cells), are lost when they are heated to 56° C for 30 minutes.

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References in periodicals archive ?
This multiplex PCR included 16s rRNA gene as internal control and genes for Panton Valentine leucocidin (PVL), toxic shock syndrome toxin, and alpha and beta hemolysins.
To corroborate the previous analysis with AP3 and 89F/R primers, multiplex PCR amplifications were done for thermolabile hemolysin (tlh), thermostable direct hemolysin (tdh), and thermostable direct hemolysin-related (trh) genes according to Bej et al.
The strains were replated on Sabouraud dextrose agar (Himedia, Mumbai, India) and incubated at 37 [degrees]C for 48 h to analyse hemolysin production.
Apart from pore-forming activity, hemolysins may have antifungal (Abe and Nakazawa 1994), anti-bacterial (Ngai and Ng 2006), and antiproliferative (Berne et al.
pseudomallei produce toxins such as pyocyanin (blue-green pigment that interferes with energy production), lecithinase (causes cell lysis), collagenase, lipase, and hemolysin.
perfringens, including four lethal toxins, hemolysins, proteases, neuraminidase and enterotoxin.
9) In this pilot study, this recommended procedure was used to screen samples of AWS water for bacteria producing hemolysins.
The spider's venom contains approximately eight separate proteins, mainly enzymes, from which levarterenol bitartrate, hemolysins, and hyaluronidase have been separated.
GAMMAGARD LIQUID contains blood group antibodies that may act as hemolysins and induce in vivo coating of red blood cells (RBC) with immune globulin.
Bt harbours many enzymes including hemolysins enterotoxins chitinases and phospholipases apart from the well documented d- endotoxins and exotoxins that help the bacteria to colonize insects (de Maagd et al.
Leptospiral hemolysins induce proinflammatory cytokines through Toll-like receptor 2-and 4-mediated JNK and NF-kappaB signaling pathways.