The present study reports a single case of a patient with Henoch-Schonlein purpura
nephritis associated with IgA-[kappa]MGRS that was gradually improved by dexamethasone and bortezomib chemotherapy.
Based on the clinical presentation, the presence of palpable skin purpura and diffuse abdominal pain with hematochezia, a clinical diagnosis of IgA vasculitis or Henoch-Schonlein Purpura
(HSP) was made.
A Case of Henoch-Schonlein Purpura
with P369S Mutation in MEFV Gene.
Lupus nephritis (LN, 8.6%), Henoch-Schonlein purpura
glomerulonephritis (HSP-GN, 4.1%), hepatitis B virus-associated nephritis (HBV-GN, 2.6%), and diabetic nephropathy (DN, 1.6%) were the most common pathological types.
In this study, the main causes were Henoch-Schonlein purpura
and CD, which are different from those in adults.
Poyrazoglu et al., "Circulating endothelial microparticles in children with Henoch-Schonlein purpura
; preliminary results," Rheumatology International, vol.
Apart from common vasculitides such as Henoch-Schonlein purpura
and Kawasaki disease, most of the primary vasculitic syndromes are rare in childhood [1-4].
The majority of reported cases within this realm describe CDIs in previously diagnosed Henoch-Schonlein purpura
(HSP) or IgA-associated vasculitis [7-9].
A classical example is represented by the Henoch-Schonlein purpura
, which causes GIB, revealed by melena, only in rare cases by haematemesis.
The etiology of acute scrotum is diverse, namely ischemia (testicular or appendiceal torsion), infection (epididymo-orchitis, abscess, Fournier's gangrene), inflammation (Henoch-Schonlein purpura
of scrotal wall and fat necrosis), trauma, and hernia (1).
The differential diagnosis of purpura fulminans includes such uncommon etiologies as Henoch-Schonlein purpura
, thrombotic thrombocytopenic purpura, drug-induced purpura, and post-infectious thrombocytopenic purpura.