The subgroups include small (41-52 amino acids, 4 disulfide linkages), medium (~70 amino acids, 6 disulfide linkages), large (~84 amino acids, 7 disulfide linkages), homodimeric and heterodimeric
NF-Bis a family of transcribing subunits likep50 p52 c-Rel Rel A (p65) and Rel B in its homo and heterodimeric
1) The members of Interleukin (IL)-12 family consisting of heterodimeric
cytokines including IL-12 and IL-27, are the most potent antitumor cytokines.
Cell adhesion is mediated by integrins, a class of heterodimeric
transmembrane cell receptors that bind selectively to different proteins of the ECM and transduce information to the nucleus through signaling pathways in the cytoplasm .
Cui M, Jiang P, Maillet E, Max M, Margolskee RF, et al (2006) The heterodimeric
sweet taste receptor has multiple potential ligand binding sites.
Integrins, which consist of an [alpha] and a [beta] subunit, are a family of heterodimeric
glycoprotein receptors on the cell surface which mediate and diversify biological communication involving cell adhesion and signal transduction .
Huang S, Gao L, Blanchoin L (2006) Heterodimeric
Capping Protein from Arabidopsis Is Regulated by Phosphatidic Acid.
Interleukin-27 (IL-27) is a heterodimeric
cytokine belonging to the IL-12 family and composed of EBI3 and p28 protein .
dependent enzymes: carboxyl-terminal binding protein (CtBP); silent information regulator (Sir2); and the heterodimeric
Clock/ NPAS2 transcriptional regulator, whose activities may play a role in ethanol-induced injury.
The result is in agreement with previous findings in which the biological active hBMP-7 was described as homodimeric or heterodimeric
forms (3), (30), (31).
A novel heterodimeric
cysteine protease is required for interleukin-1 beta processing in monocytes.
Ricin is a ribosome inactivating protein (RIP) consisting of a heterodimeric
polypeptide able to inactivate 1500 ribosome per minute, which interrupts protein synthesis and leads to cell death.