heteroduplex

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heteroduplex

[‚hed·ə·rō′dü‚pleks]
(genetics)
A double-stranded deoxyribonucleic molecule comprising strands from different individuals.
(cell and molecular biology)
A double-stranded molecule of deoxyribonucleic acid in which the two strands show noncomplementary sections.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive ?
Seminested polymerase chain reaction and heteroduplex analysis detects the monoclonality of IgH rearrangement in follicular lymphoma patients with high sensitivity.
Identification and characterization of new BoLA DRB3 alleles by heteroduplex analysis and direct sequencing.
The PCR products of all exons were screened for variations by heteroduplex analysis. In PCR products of exon 8 of patients III-5 and III-9 and the females II-1, II-2, II-4, II-5, III-4 and III-8 were found shift bands using heteroduplex analysis.
Heteroduplex analysis, a method discontinued in 2002, identified four additional mutations found with elevated frequency in African Americans.
Heteroduplex analysis demonstrated that in each population, each mobility class did indeed share the same sequence with those same mobility classes in other populations.
The automated analysis used the heteroduplex analysis plug-in for BioNumerics software (version 5.10; Applied Maths) (23).
Heteroduplex Analysis of T-Cell Receptor [Gamma] Gene Rearrangement
In cases in which homozygotes are difficult to distinguish, amplicon-melting analysis can still provide complete genotyping information via their mixing with a known homozygote followed by quantitative heteroduplex analysis (13).
Polymerase chain reaction products can be detected by agarose and polyacrylamide gel electrophoresis, single-strand conformational polymorphism, heteroduplex analysis, denaturing gradient gel electrophoresis (DGGE), temperature gradient gel electrophoresis (TGGE), and capillary gel electrophoresis.[5-12]