Hirschsprung's disease

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Hirschsprung's disease

[′hərsh‚pru̇ŋz di‚zēz]
(medicine)
A disease caused by absence of the myenteric ganglion cells in a segment of rectum or distal colon, resulting in spasm of the affected part and dilation of the bowel proximal to the defect.
References in periodicals archive ?
Hirschprung's disease is a condition in which some of the nerves supplying the lower bowel have failed to develop properly and so the lower bowel does not function normally and causes an obstruction.
Bowel function, mental health and psychosocial function in adolescents with Hirschprung's disease.
An example is the treatment of Hirschprung's disease, a life-threatening bowel disorder that affects infants.
This bacterial infection resulted in septicemia secondary to the Hirschprung's disease also known as Congenital Aganglionic Megacolon causing functional colonic obstruction resulting in severe constipation and abdominal distension.