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The developmental process by which the definite cells and tissues which make up the body of an organism arise from embryonic cells.



the development of tissues; the complex of natural processes that ensures the emergence, existence, and restoration of animal tissues and their specific properties in various organs.

The study of the histogenesis of various tissues and its principles is one of the most important aspects of histology. The term “histogenesis” is customarily used to designate the ontogenetic development of tissues. However, the patterns of histogenesis cannot be regarded separately from the evolutionary development of tissues. The basis of histogenesis is cell differentiation (the development of growing morphological and functional differences between newly specializing cells), which begins during the earliest stages of embryonic development. This is a complex molecular-genetic process that regularly involves the activity of the genes that determine the specifics of protein syntheses in the cell. The multiplication of cells, their relative migrations, and other processes lead to the formation of embryonic rudiments, which consist of groups of cells distributed according to a regular pattern in the body of the embryo. The entire diversity of tissues of various organs of the body arises as a result of the tissue differentiation of these embryonic rudiments.

During the postembryonic period the processes of histogenesis are divided into three basic types: the processes within tissues whose cells do not multiply (for example, in nervous tissue), those in tissues whose cell division is associated primarily with the growth of the organ (for example, in the parenchyma of the digestive glands and kidneys), and those in tissues characterized by constant cell renewal (for example, in hemopoietic tissue and many integumental epithelia). Cells that effect definite histogenesis are subdivided into a series of successive groups, including a stock of parent cells, capable of differentiation as well as of making up a loss of its own kind; a stock of precursor cells that undergo differentiation and are capable of division; and a stock of mature cells that have completed differentiation. The regeneration of damaged or partially depleted tissues after injury is accomplished through so-called reparative histogenesis. Under pathological conditions the processes of histogenesis may undergo profound qualitative changes and lead to the development of tumorous tissues.


Khlopin, N. G. Obshchebiologicheskie i eksperimental’nye osnovy gistologii. Moscow, 1946. (Bibliography.)
Zavarzin, A. A. “Ocherki evoliutsionnoi gistologii krovi i soedinitel’noi tkani.” Izbr. trudy, vol. 4. Moscow-Leningrad, 1953.
Krushchov, N. G. Funktsional’naia tsitokhimiia rykhloi soedi nitel’noi tkani. Moscow, 1969. (Bibliography.)


References in periodicals archive ?
It is worth noting that cataphylls lacking distal leaf identity have no defects in the abaxial-adaxial domains or in the regular histogenesis and morphogenesis typical of the leaf base (Figs.
Over 100 different primary andbodies have been evaluated using IHC on KS specimens in order to unravel the histogenesis of KS, understand its pathogenesis, facilitate diagnosis, and help identify novel therapeutic targets [80].
has patented a unique design of sophisticated negative pressure technology that leads to the first controlled and repeatable method of soft tissue histogenesis.
These substances induce cellular death in histogenesis and different morphogenetic processes, such as the integrative mechanisms in the modeling of form during the dorsoventral organization.
For example, the poor outcome marker Bcl-2 more likely segregates with immunoblastic tumors of postgerminal center origin and predicts poor prognosis compared to the Burkitt's and centroblastic tumors, both of which are more likely associated with germinal center histogenesis and a better prognosis.
Stem cells in the embryonic cerebral cortex: Their role in histogenesis and patterning.
Cytogenesis and histogenesis of the inferior olive, pontine gray, and the pre-cerebellar reticular nuclei.
Renal oncocytoma: A review of histogenesis, histopathology, diagnosis and treatment.
Hemangiopericytoma is a tumor of uncertain histogenesis.
The first studies that were about bone histogenesis were done by Brachet [4] but it was done thoroughly in before and after hatching time [9, 31].
23,25) The histogenesis of calcifications specifically associated with LCIS/ALH is unclear and one alternate possibility is that in some cases, LCIS/ALH secondarily involves ducts and lobules already populated by calcifications.
Samaha M, Woodruff J D: Paratubal cysts: frequency, histogenesis, and associated clinical features.