holoenzyme

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Related to Holoenzymes: Isoenzymes, Apoenzymes

holoenzyme

[¦häl·ō′en‚zīm]
(biochemistry)
A complex, fully active enzyme, containing an apoenzyme and a coenzyme.
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But if holoenzymes prove essential in yeast, transcription in other eukaryotic organisms, including mammals, should work similarly, says Ronald C.
Koleske have evidence that, in yeast, several SRB proteins chair a committee - called a holoenzyme - that includes RNA polymerase and several other substances important for reading the genetic code.
Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides.