Holtfreter, Johannes

Holtfreter, Johannes (Friedrich Karl)

(1901–  ) embryologist; born in Richtenberg, Germany. He taught in Germany (1928–38), emigrated to McGill University, Montreal (1942–46), then came to the U.S.A. to join Rochester University (1946–69). After over 40 years investigating morphogenesis and differentiation in amphibian, avian, and mammalian embryos, he concluded that development of specialized organs from the undifferentiated early embryo is the result of both directed cell movement and separations and reassociations controlled by selective cell adhesion.